124093-19-2Relevant academic research and scientific papers
Experimental and DFT 1H NMR study of conformational equilibria in trans-4′,7-dihydroxyisoflavan-4-ol and trans-isoflavan-4-ol
Pihlaja, Kalevi,Taehtinen, Petri,Klika, Karel D.,Jokela, Tuija,Salakka, Auli,Waehaelae, Kristiina
, p. 6864 - 6869 (2003)
The solution-state conformational equilibria of trans-4′ ,7-dihydroxyisoflavan-4-ol (1) and transisoflavan-4-ol (2) were assessed based on the temperature dependence of their vicinal coupling constants J H-2α,H-3 and JH-3,H-4 in comp
The Synthesis, Structure, and Anticancer Activity of cis- and trans-4',7-Dihydroxyisoflavan-4-ols
Waehaelae, Kristiina,Koskimies, Jorma K.,Mesilaakso, Markku,Salakka, Auli K.,Leino, Tero K.,Adlercreutz, Herman
, p. 7690 - 7693 (1997)
cis-4',7-Dihydroxyisoflavan-4-ol (4) and trans-4',7-dihydroxyisoflafan-4-ol (5), two proposed metabolites of daidzein (4',7-dihydroxyisoflavone), have been synthesized and fully characterized for the first time.The vicinal coupling constants of the pyran
ENZYME ASSOCIATED WITH EQUOL SYNTHESIS
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, (2011/01/05)
An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.
Production of isoflavone derivatives
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Page/Page column 12, (2008/06/13)
Methods for the hydrogenation of isoflavones are described which provide access to workable quantities of isoflavan-4-ols, isoflav-3-enes, and isoflavans. The isoflavone derivatives can be obtained in high purity and in near quantitative yields whilst employing pharmaceutically acceptable reagents and solvents.
HYDROGEN TRANSFER REDUCTION OF ISOFLAVONES
Waehaelae, K.,Hase, T. A.
, p. 183 - 186 (2007/10/02)
Hydrogen transfer reduction of isoflavones using ammonium formate and palladium charcoal provides an easy access to polyoxyisoflavanones and also to isoflavan-4-ols without the need for protection of the hydroxy groups.Optimized reaction conditions for im
