81267-09-6Relevant articles and documents
Enantioselective Synthesis of Isoflavanones by Catalytic Dynamic Kinetic Resolution
Qin, Tao,Metz, Peter
supporting information, p. 2981 - 2984 (2017/06/07)
A ruthenium-catalyzed asymmetric transfer hydrogenation of racemic isoflavanones with dynamic kinetic resolution yields virtually enantiopure isoflavanols as single diastereomers. Subsequent oxidation gives rise to isoflavanones in high enantiomeric purit
Synthesis of oxygenated 4-arylisoflavans and 4-arylflavans
Deodhar, Mandar,Wood, Kasey,Black, David Stc,Kumar, Naresh
, p. 6697 - 6700,4 (2012/12/13)
Oxygenated 4-arylisoflavans and 4-heteroarylisoflavans were synthesized in good yields via BF3·OEt2 catalyzed arylation reactions of 4′,7-diacetoxyisoflavan-4-ol 8 with activated aryl and heteroaryl compounds. These reactions were found to produce stereoselectively the trans isomers. Similar reactions of 4′,7-diacetoxyflavan-4-ol 16 afforded the corresponding 4-arylflavans and 4-heteroarylflavans as mixtures of cis/trans isomers.
Production of isoflavone derivatives
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Page/Page column 13, (2008/06/13)
Methods for the hydrogenation of isoflavones are described which provide access to workable quantities of isoflavan-4-ols, isoflav-3-enes, and isoflavans. The isoflavone derivatives can be obtained in high purity and in near quantitative yields whilst employing pharmaceutically acceptable reagents and solvents.