124141-45-3

Upstream product

• 110-86-1 pyridine 
• 7664-93-9 sulfuric acid 
• 35476-69-8 1,1-diphenyl-3-p-methoxyphenylpropargyl alcohol 
• 696-62-8 para-iodoanisole 
• 119-61-9 benzophenone 
• 768-60-5 4-methoxyphenylacetylen 
• 776-74-9 Bromodiphenylmethane 
• 90-99-3 diphenylchloromethane 
• 115679-97-5 1,1-Bis(4-methoxyphenyl)-3,3-diphenylpropene 

Downstream Products

• 119482-41-6 (+/-)-7-benzhydryl-9-methoxy-8-(4-methoxy-phenyl)-(4ar)-1,2,3,4,4a,5-hexahydro-1t,4t-etheno-naphthalene-2c,3c,5t,6t-tetracarboxylic acid-2,3;5,6-dianhydride 
• 119482-41-6 (+/-)-7-benzhydryl-9-methoxy-8-(4-methoxy-phenyl)-(4ar)-1,2,3,4,4a,5-hexahydro-1t,4t-etheno-naphthalene-2t,3t,5t,6t-tetracarboxylic acid-2,3;5,6-dianhydride 

Relevant academic research and scientific papers

Synthesis of tetraarylallenes via palladium-catalyzed addition-elimination reactions of 1,1,3-triaryl-2-propyn-1-ols with aryl iodides

The palladium-catalyzed reactions of tert-propargylic alcohols with aryl iodides afforded tetraarylallenes in good yields. This reaction involves: (1) oxidative addition of the aryl iodide to Pd(O); (2) arylpalladium intermediate coordination to the carbon-carbon triple bond of the 1,1,3-triaryl-2-propyn-1-ol and subsequent regioselective insertion of the alkynol to form β-hydroxyvinylpalladium species; and (3) β-elimination to produce the tetraarylallenes. Generally, the best results are obtained by employing 5 mol% of Pd(TFA)2, 10 mol% of PPh3, two equivalents of aryl iodide and five equivalents of Et3N in MeCN. Georg Thieme Verlag Stuttgart.