124211-67-2

Upstream product

• 124211-66-1 2-phenyl-4-(4-phenylbutyl)-1,3,2-benzodioxaborin 
• 18328-11-5 3-benzyl propionaldehyde 
• 167145-22-4 1-Benzyloxy-2-((E)-5-phenyl-pent-1-enyl)-benzene 
• 36884-28-3 5-phenyl-1-pentanal 
• 108-95-2 phenol 

Relevant academic research and scientific papers

[2-ω-phenylalkyl)phenoxy]alkylamines: Synthesis and dual dopamine2 (D2) and 5-hydroxytryptamine2 (5-HT2) receptor antagonistic activities

A series of [2-(ω-phenylalkyl)phenoxy]alkylamines was synthesized and their 5-hydroxytryptamine2 (5-HT2) and/or dopamine2 (D2) receptor antagonistic activities were examined in vitro. [2-(4- Phenylbutyl)phenoxy]

ortho-Specific alkylation of phenols via 1,3,2-benzodioxaborins

Reaction of a phenol with an aldehyde in the presence of phenylboronic acid gives a 1,3,2-benzodioxaborin.The latter could be reduced to the corresponding ortho-alkylphenol with tert-butylamine borane in the presence of aluminum chloride.Alternatively, the dioxaborin, when reacted with an alkylthiol or an alcohol in the presence of an acid, gave the corresponding ortho-alkylthiomethyl- or ortho-alkoxymethylphenol.Key words: phenol, alkylation, ortho-specific, 1,3,2-benzodioxaborin.