124236-29-9

Usage

Uses

Different sources of media describe the Uses of 124236-29-9 differently. You can refer to the following data:
1. Crotamiton is an anti-parasitic agent. Crotamiton is used both as a scabicidal (for treating scabies) and as a general antipruritic.
2. Crotamiton was used to study the photocatalytic decomposition of crotamiton in aqueous solution using TiO2. N-Ethyl-o-crotonotoluidide (Crotamiton) was used to treat scabies and various pruritic dermatoses.

Upstream product

• 94-68-8 N-ethyl-2-methylaniline 
• 10487-71-5 crotonyl chloride 
• 107-93-7 (E)-but-2-enoic acid 
• 625-35-4 trans-chrotonyl chloride 

Downstream Products

• 1257630-45-7 potassium N-ethyl-N-(o-tolyl)-3-(trifluoroborato)butanamide 
• 1257558-12-5 3-(4-(1H-pyrrol-1-yl)phenyl)-N-ethyl-N-(o-tolyl)butanamide 
• 1577257-94-3 N-ethyl-3-hydroxy-N-(o-tolyl)butanamide 
• 1577257-95-4 (R)-N-ethyl-3-hydroxy-N-(o-tolyl)butanamide 

Relevant academic research and scientific papers

Trans N-ethyl-N-(2 the [...] -alkyl-phenyl) - 2-butenamide synthetic method

The invention relates to a synthesis method for trans N-ethyl-N-(2'-alkyl phenyl)-2-butenamide. The method comprises the steps of: 1) adding trans 2- butenoic acid into a reaction bottle, conducting dilution with an alkane solvent, performing cooling to 0-10DEG C, adding thionyl chloride dropwise, and then carrying out reaction at 10-50DEG C for 3-4h for standby use; 2) adding N-ethyl-2-alkyl aniline into the reaction bottle, conducting dilution with an alkane solvent, adding an alkaline aqueous solution, subjecting the mixed solution to stirring reaction at room temperature, adding the mixed solution obtained in step 1) slowly in a dropwise manner, and then carrying out reaction at 60-90DEG C for 5-6h at the end of dropwise adding; and 3) at the end of the reaction, separating out the organic phase, and washing the organic phase to neutral by water, conducting room temperature distillation to remove the solvent, and then performing pressure reduced distillation to separate the product. The method is simple, has high product yield, and can produce the high purity trans-structure product.

PACKAGING BAG FOR PLASTER AND PACKAGED PLASTER

Packaged patch (10) according to the invention comprises patch (2) situated in space (4) inside patch package (3) composed of laminated packaging material (1), and its edges are sealed. Laminated packaging material (1) comprises hygroscopic material layer (13) made of LDPE containing 20-40 wt% of an inorganic filler, situated between moisture-permeable material layer (14) made of LDPE and having a moisture permeability of 40-120 g/m2/day and a screen material layer which blocks penetration of moisture, etc. and is composed of HDPE layer (12) and aluminum foil (11). The saturation hygroscopicity of laminated packaging material (1) is 2-30 g/m2under atmosphere conditions with a temperature of 25°C and a relative humidity of 75%. This construction sufficiently reduces the effect of moisture on a drug in patch (2) and allows patch (2) to be held in a stable state for prolonged periods, while also improving the economy and handleability of patch package (3).