124256-80-0

Upstream product

• 6859-99-0 3-hydroxypiperazine 
• 647863-16-9 (RS)-3-hydroxy-1-N-tritylpiperidine 
• 124-63-0 methanesulfonyl chloride 
• 76-83-5 trityl chloride 

Downstream Products

• 1271239-90-7 (RS)-3-(cytosin-2-O-yl)-1-N-tritylpiperidine 
• 1271239-87-2 2-(adenin-9-yl)methyl-1-N-tritylpyrrolidine 
• 1271239-78-1 (RS)-3-(adenin-9-yl)-1-N-tritylpiperidine 
• 1271239-83-8 2-(thymin-1-yl)methyl-1-N-tritylpyrrolidine 
• 1271239-96-3 (RS)-3-(thymin-1-yl)-1-N-tritylpiperidine 

Relevant academic research and scientific papers

The synthesis of piperidine nucleoside analogs - A comparison of several methods to access the introduction of nucleobases

This work deals with the synthesis of piperidine and hydroxypiperidine analogs of nucleosides. Starting from commercially available 3-hydroxypiperidine, proline or 4-hydroxyproline, a series of piperidine derivatives of both purine and pyrimidine nucleobases was prepared. Various methods of nucleobase attachment were evaluated. The prepared compounds were tested for cytostatic, antibacterial, and antiviral properties but no significant activity was found.