124325-90-2

Basic information

• Product Name: 3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyric acid ethyl ester
• Synonyms: 3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyric acid ethyl ester
• CAS NO: 124325-90-2
• Molecular Weight: 423.349
• Mol File: 124325-90-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyric acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyric acid ethyl ester(124325-90-2)
• EPA Substance Registry System: 3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyric acid ethyl ester(124325-90-2)

Safety Data

• Hazardous Substances Data: 124325-90-2(Hazardous Substances Data)

Upstream product

• 190729-08-9 (E)-3-(4'-Bromo-biphenyl-4-yl)-acrylic acid ethyl ester 
• 6921-34-2 benzylmagnesium chloride 
• 50670-58-1 4-formyl-4'-bromobiphenyl 
• 92-86-4 4-(4-bromophenyl)bromobenzene 
• 103-80-0 phenylacetyl chloride 
• 60312-95-0 1-[4'-bromo(1,1'-biphenyl)-4-yl]-2-phenylethan-1-one 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 124325-88-8 3-(4'-bromo-biphenyl-4-yl)-3-hydroxy-4-phenyl-butyric acid ethyl ester 

Downstream Products

• 70942-04-0 1-Bromo-3-(4'-bromo-biphenyl-4-yl)-1,2,3,4-tetrahydro-naphthalene 
• 56181-82-9 (+/-)-cis/trans-3-(4''-Bromobiphenyl-4'-yl)-1,2,3,4-tetrahydronaphthalen-1-ol 
• 124325-89-9 3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyric acid 
• 60313-01-1 3-(4''-Bromobiphenyl-4'-yl)-1,2,3,4-tetrahydronaphthalen-1-one 

Relevant articles and documents

Synthesis and antitumor activity of 4-hydroxycoumarin derivatives

A series of 4-hydroxycoumarin derivatives was prepared and evaluated for antitumor activity against five human tumor cell lines. A series of 4-hydroxycoumarin derivatives was prepared and evaluated for antitumor activity. The key fragments were 2a-c, 5c, 12b, 13b, 17, and 18 which were prepared via dianion ring cyclization, Friedel-Crafts acylation, and Reformatsky reaction. Compound 20b showed the most potent antitumor activity among the total 12 derivatives and compounds 19a and 19b exhibited efficacy comparable to etoposide in vitro antitumor activity.