124337-89-9

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 68269-56-7 3-methyl-3-vinylcyclohexan-1-one 
• 124337-85-5 α,α-dimethyl-1-(p-toluenesulfonyl)-1H-indole-4-methanol 
• 102308-02-1 Δ^1.2-1-triemthylsilyloxy-3-methyl-3-vinylcyclohexene 
• 124337-86-6 Δ^1.6-1-triemthylsilyloxy-3-methyl-3-vinylcyclohexene 
• 124337-87-7 5-Methyl-2-{1-methyl-1-[1-(toluene-4-sulfonyl)-1H-indol-4-yl]-ethyl}-5-vinyl-cyclohexanone 

Downstream Products

• 106865-64-9 (+/-)-hapalindole M 2 
• 124337-95-7 6a-Methoxy-6,6,9-trimethyl-2-(toluene-4-sulfonyl)-9-vinyl-2,6,6a,7,8,9-hexahydro-2-aza-aceanthrylene 
• 124337-94-6 10-Methoxy-6,6,9-trimethyl-2-(toluene-4-sulfonyl)-9-vinyl-2,6,7,8,9,10-hexahydro-2-aza-aceanthrylene 
• 131573-12-1 2,6,7,8,9,10-hexahydro-10ξ-hydroxy-6,6,9-trimethyl-2-p-toluenesulfonyl-9-vinylnaphth<1,2,3-cd>indole 
• 131572-81-1 rac-(R)-6,6,9-trimethyl-2-tosyl-9-vinyl-6,7,8,9-tetrahydronaphtho[1,2,3-cd]indol-10(2H)-one 
• 124337-93-5 6,6,9-Trimethyl-2-(toluene-4-sulfonyl)-10-vinyl-2,6-dihydro-2-aza-aceanthrylene 
• 131572-74-2 2,6,6a,7,8,9-hexahydro-6ξ-hydroxy-6,6,9-trimethyl-2-p-toluenesulfonyl-9-vinylnaphth<1,2,3-cd>indole 

Relevant academic research and scientific papers

Synthetic studies on the ambiguine family of alkaloids: Construction of the ABCD ring system

A racemic synthesis of the ABCD ring core of the ambiguines that preserves the tertiary alcohol has been accomplished in a convergent synthesis in 10 synthetic steps, in an overall yield of 46% from commercially available 4-bromoindole and m-methylanisole

SYNTHETIC STUDIES OF MARINE ALKALOIDS HAPALINDOLES. Part 1. TOTAL SYNTHESIS OF (+/-)-HAPALINDOLES J and M

The first concise synthesis of marine indole alkaloids (+/-) hapalindoles J (4) and M (5) was achieved in seven or six steps starting from a readily available compound 6 using important key reactions, 6 -> 7 -> 8 and 35 -> 41 or 5.

TOTAL SYNTHESIS OF MARINE ALKALOIDS (+/-)-HAPALINDOLES J AND M

Marine alkaloids hapalindoles J 1 and M 2 were concisely synthesized in the racemic form from a tertiary alcohol 4 by way of 7, 9, 11, and 17, using unusual LiAlH4 reduction of 11 as a key reaction step.