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CAS

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124340-66-5

2-Biphenyl-4-yl-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 124340-66-5 Structure

  • Basic information

    1. Product Name: 2-Biphenyl-4-yl-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide
    2. Synonyms: 2-Biphenyl-4-yl-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide
    3. CAS NO:124340-66-5
    4. Molecular Formula:
    5. Molecular Weight: 384.481
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 124340-66-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-Biphenyl-4-yl-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-Biphenyl-4-yl-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide(124340-66-5)
    11. EPA Substance Registry System: 2-Biphenyl-4-yl-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide(124340-66-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 124340-66-5(Hazardous Substances Data)

124340-66-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 124340-66-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,3,4 and 0 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 124340-66:
(8*1)+(7*2)+(6*4)+(5*3)+(4*4)+(3*0)+(2*6)+(1*6)=95
95 % 10 = 5
So 124340-66-5 is a valid CAS Registry Number.

124340-66-5Downstream Products

124340-66-5Relevant articles and documents

Potential Antitumor Agents. 59. Structure-Activity Relationships for 2-Phenylbenzimidazole-4-carboxamides, a New Class of "Minimal" DNA-Intercalating Agents Which May Not Act via Topoisomerase II

Denny, William A.,Rewcastle, Gordon W.,Baguley, Bruce C.

, p. 814 - 819 (2007/10/02)

A series of substituted 2-phenylbenzimidazole-4-carboxamides has been synthesized and evaluated for in vitro and in vivo antitumor activity.These compounds represent the logical conclusion to our search for "minimal" DNA-intercalating agents with the lowest possible DNA-binding constants.Such "2-1" tricyclic chromophores, of lower aromaticity than the structurally similar 2-phenylquinolines, have the lowest DNA binding affinity yet seen in the broad series of tricyclic carboxamide intercalating agents.Despite very low in vitro cytotoxicities, several of the compoundshad moderate levels of in vivo antileukemic effects.However, the most interesting aspect of their biological activity was the lack of cross-resistance shown to an amsacrine-resistant P388 cell line, suggesting that these compounds may not express their cytotoxicity via interaction with topoisomerase II.

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