124341-05-5

Basic information

• Product Name: 2-Azidocarbonyl-3-nitro-benzoic acid ethyl ester
• Synonyms: 2-Azidocarbonyl-3-nitro-benzoic acid ethyl ester
• CAS NO: 124341-05-5
• Molecular Weight: 264.197
• Mol File: 124341-05-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Azidocarbonyl-3-nitro-benzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azidocarbonyl-3-nitro-benzoic acid ethyl ester(124341-05-5)
• EPA Substance Registry System: 2-Azidocarbonyl-3-nitro-benzoic acid ethyl ester(124341-05-5)

Safety Data

• Hazardous Substances Data: 124341-05-5(Hazardous Substances Data)

Upstream product

• 136285-66-0 3-nitro-phthalic acid-1-ethyl ester-2-chloride 
• 603-11-2 3-nitrophthalic acid 
• 75-65-0 tert-butyl alcohol 
• 16533-45-2 ethyl 2-carboxy-3-nitrobenzoate 

Downstream Products

• 136285-65-9 ethyl 2-[(N-tert-butoxycarbonyl)amino]-3-nitrobenzoate 
• 603-81-6 2,3-diaminobenzoic acid 
• 124340-67-6 2-(4-Acetylamino-phenyl)-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide 
• 124340-75-6 2-(2,3-Dimethoxy-phenyl)-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide 
• 124340-66-5 2-Biphenyl-4-yl-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide 
• 124340-55-2 2-(2-Methoxy-phenyl)-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide 
• 124340-68-7 2-(4-Dimethylamino-phenyl)-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide 
• 124340-56-3 2-(2-Chloro-phenyl)-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide 
• 124340-63-2 2-(4-Methoxy-phenyl)-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide 
• 124340-59-6 N'-<2-(N,N-dimethylamino)ethyl>-2-(3'-methoxyphenyl)-1H-benzimidazole-4-carboxamide 
• 124340-54-1 2-o-Tolyl-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide 
• 124340-64-3 2-(4-Chloro-phenyl)-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide 
• 124340-60-9 2-(3-Chloro-phenyl)-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide 
• 124340-62-1 2-p-Tolyl-1H-benzoimidazole-4-carboxylic acid (2-dimethylamino-ethyl)-amide 

Relevant articles and documents

Synthesis Method for Candesartan Cilexetil Intermediate

A synthesis method for a candesartan cilexetil intermediate represented by formula (II) is provided. The method includes (1) dissolving a compound represented by formula (IV) to an aprotic solvent to obtain a first mixed solution, and dissolving a phase transfer catalyst and an azidation reagent to water to obtain a second mixed solution; (2) dropping the first mixed solution to the second mixed solution for azidation reaction, and after the reaction is ended, standing and layering same to obtain an organic phase containing a compound represented by formula (V); (3) dropping the obtained organic phase containing the compound represented by formula (V) to tertiary butyl alcohol for rearrangement reaction, and after the reaction is ended, concentrating same to obtain a solid or oily material, then adding a crystallizing solvent to the obtained solid or oily material for recrystallization, and separating same to obtain a crystal.