124356-90-7

Upstream product

• 124356-84-9 <3(2S,4R,5R),4S>-3-(1,3-dioxo-5-hydroxy-2,4,6-trimethyl-6-heptenyl)-4-(phenylmethyl)-2-oxazolidinone 
• 124356-89-4 (2S,3R,4S,5R)-2,4,6-trimethyl-3,5-[(bis-dimethylmethylene)dioxy]hept-6-enal 
• 124356-94-1 <4R,5S,6S,(1R)>-4-(1-methylethenyl)-6-(2-hydroxy-1-methylethyl)-2,2,5-trimethyl-1,3-dioxane 
• 124379-81-3 (4S)-4-benzyl-3-<(2S,4R,5S,6R)-5-hydroxy-6-<(4S,5R,6R)-6-isopropenyl-2,2,5-trimethyl-1,3-dioxan-4-yl>-2,4-dimethyl-3-oxoheptanoyl>-2-oxazolidinone 
• 333-27-7 methyl trifluoromethanesulfonate 

Downstream Products

• 129618-45-7 (2S,4R,5S,6R)-1-((S)-4-Benzyl-2-oxo-oxazolidin-3-yl)-6-[(4S,5R,6S)-6-((R)-2-hydroxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-5-methoxy-2,4-dimethyl-heptane-1,3-dione 
• 129618-45-7 (2S,4R,5S,6R)-1-((S)-4-Benzyl-2-oxo-oxazolidin-3-yl)-6-[(4S,5R,6S)-6-((S)-2-hydroxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-5-methoxy-2,4-dimethyl-heptane-1,3-dione 
• 129618-46-8 (S)-2-{(4R,5S,6S)-6-[(1R,2S,3R,5S)-6-((S)-4-Benzyl-2-oxo-oxazolidin-3-yl)-2-methoxy-1,3,5-trimethyl-4,6-dioxo-hexyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-propionaldehyde 
• 129618-44-6 (S)-4-Benzyl-3-((S)-2-{(2R,3R,4S,5R,6S)-2,4-dimethoxy-3,5-dimethyl-6-[(R)-1-((4R,5R)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetrahydro-pyran-2-yl}-propionyl)-oxazolidin-2-one 
• 129618-44-6 (S)-4-Benzyl-3-((S)-2-{(2R,3R,4S,5R,6S)-2,4-dimethoxy-3,5-dimethyl-6-[(R)-1-((4R,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetrahydro-pyran-2-yl}-propionyl)-oxazolidin-2-one 
• 162255-00-7 (4S)-4-benzyl-3-<(2S)-2-<(2R,3R,4S,5R,6R)-tetrahydro-6-<(1R,2R)-2-hydroxy-1,3-dimethyl-3-butenyl>-2,4-dimethoxy-3,5-dimethyl-2H-pyran-2-yl>propionyl>-2-oxazolidinone 

Relevant academic research and scientific papers

Mild alcohol methylation procedure for the synthesis of polyoxygenated natural products. Applications to the synthesis of lonomycin a

Studies directed toward the formation of methyl ethers in key intermediates for the synthesis of lonomycin A are described. Several highly functionalized secondary alcohols have been methylated in excellent yields using the powerful methylating reagents m

Total synthesis of the polyether antibiotic lonomycin A (Emericid)

The first asymmetric synthesis of the polyether antibiotic lonomycin has been achieved. The skeleton is assembled through the synthesis and union of two subunits comprising the C1-C11 and C12-C30 portions of the