Mild alcohol methylation procedure for the synthesis of polyoxygenated natural products. Applications to the synthesis of lonomycin a

Article abstract of DOI:10.1016/0040-4039(94)85352-5

Studies directed toward the formation of methyl ethers in key intermediates for the synthesis of lonomycin A are described. Several highly functionalized secondary alcohols have been methylated in excellent yields using the powerful methylating reagents m