124371-52-4

Upstream product

• 124371-61-5 methyl 2-(phenylmethylsulfanyl)-3,5-dinitrobenzenecarboxylate 
• 475096-00-5 2-(phenylmethylsulfanyl)-3,5-dinitrobenzenecarboxylic acid 
• 100-53-8 phenylmethanethiol 
• 2497-91-8 2-chloro-3,5-dinitrobenzoic acid 

Downstream Products

• 23621-08-1 benzo[1,2,3]thiadiazole-7-carboxylic acid methtyl ester 
• 35272-27-6 benzo[d][1,2,3]thiadiazole-7-carboxylic acid 
• 124371-49-9 benzothiadiazole-7-carboxylic acid chloride 
• 135158-54-2 S-methyl-benzo[1,2,3]thiadiazole-7-carbothioate 

Relevant academic research and scientific papers

Derivatives of benzothiadiazole-7-carboxylates: Synthesis and biological activity

Salicylic acid (SA) and methyl jasmonate (MJ) are important plant signal molecules to cause systemic acquired resistance (SAR), while it's reported that they also have wide spectrum antitumor activities. Benzothiadiazole-7- carboxylates are plant activators which can cause SAR just like SA and MJ. To investigate whether the benzothiadiazole-7-carboxylate family is endowed with anticancer activities, several benzothiadiazole-7-carboxylate derivatives are synthesized and their inhibition to P388 murine leukemia cell and A549 human lung cancer cell compared with MJ are evaluated. The data indicated that benzo-1,2,3-thiadiazole-7-carboxylic acid 2-benzoyloxyethyl ester has a higher inhibition ability to the cancer cell P388 and A549, compared with MJ.

The chemistry of benzothiadiazole plant activators

Systemic Acquired Resistance (SAR) is an inducible resistance mechanism in plants that, together with other defence mechanisms, provides broadspectrum and long-lasting disease control. With novel screening techniques the benzo[1,2,3]thiadiazole-7-carboxylic acid derivatives have been identified as a new class of chemicals which stimulate the plant's own defence mechanisms. The synthesis and biological activities of various benzo[1,2,3]thiadiazoles and related structures are described. S-Methyl benzo[1,2,3]thiadiazole-7-carbothioate is the first synthetic chemical 'plant activator' that has been developed for this novel disease control concept.

Process and a composition for immunizing plants against diseases

A method and composition for the immunization of healthy useful plants against plant diseases containing as active ingredients compounds of formula STR1 in which: X is hydrogen, halogen, hydroxy, methyl, methoxy, HOOC or MOOC; Y is hydrogen, halogen, SO3 H, SO3 M, nitro, hydroxy or amino, M being the molar equivalent of an alkali metal or alkaline earth metal ion that is formed from a corresponding base or basic compound; and Z is cyano or --CO--A; A represents either --OH or --SH, the hydrogen atom of which may also be replaced by the molar equivalent of an inorganic or organic cationic residue, or wherein A represents any other organic residue which has a molecular weight of less than 900 and which may also contain one, or more than one, hetero atom, including the salts of the phytophysiologically tolerable 7-carboxylic acid or 7-thiocarboxylic acid with primary, secondary or tertiary amines or with inorganic bases.