124371-61-5

Basic information

• Product Name: methyl 2-(phenylmethylsulfanyl)-3,5-dinitrobenzenecarboxylate
• Synonyms: methyl 2-(phenylmethylsulfanyl)-3,5-dinitrobenzenecarboxylate
• CAS NO: 124371-61-5
• Molecular Weight: 348.336
• Mol File: 124371-61-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 2-(phenylmethylsulfanyl)-3,5-dinitrobenzenecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(phenylmethylsulfanyl)-3,5-dinitrobenzenecarboxylate(124371-61-5)
• EPA Substance Registry System: methyl 2-(phenylmethylsulfanyl)-3,5-dinitrobenzenecarboxylate(124371-61-5)

Safety Data

• Hazardous Substances Data: 124371-61-5(Hazardous Substances Data)

Upstream product

• 2497-91-8 2-chloro-3,5-dinitrobenzoic acid 
• 100-53-8 phenylmethanethiol 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 
• 475096-00-5 2-(phenylmethylsulfanyl)-3,5-dinitrobenzenecarboxylic acid 

Downstream Products

• 35272-27-6 benzo[d][1,2,3]thiadiazole-7-carboxylic acid 
• 124371-49-9 benzothiadiazole-7-carboxylic acid chloride 
• 135158-54-2 S-methyl-benzo[1,2,3]thiadiazole-7-carbothioate 
• 23621-08-1 benzo[1,2,3]thiadiazole-7-carboxylic acid methtyl ester 
• 124371-52-4 2-benzylthio-3,5-diamino-benzoic acid methyl ester 

Relevant articles and documents

Derivatives of benzothiadiazole-7-carboxylates: Synthesis and biological activity

Salicylic acid (SA) and methyl jasmonate (MJ) are important plant signal molecules to cause systemic acquired resistance (SAR), while it's reported that they also have wide spectrum antitumor activities. Benzothiadiazole-7- carboxylates are plant activators which can cause SAR just like SA and MJ. To investigate whether the benzothiadiazole-7-carboxylate family is endowed with anticancer activities, several benzothiadiazole-7-carboxylate derivatives are synthesized and their inhibition to P388 murine leukemia cell and A549 human lung cancer cell compared with MJ are evaluated. The data indicated that benzo-1,2,3-thiadiazole-7-carboxylic acid 2-benzoyloxyethyl ester has a higher inhibition ability to the cancer cell P388 and A549, compared with MJ.

The chemistry of benzothiadiazole plant activators

Systemic Acquired Resistance (SAR) is an inducible resistance mechanism in plants that, together with other defence mechanisms, provides broadspectrum and long-lasting disease control. With novel screening techniques the benzo[1,2,3]thiadiazole-7-carboxylic acid derivatives have been identified as a new class of chemicals which stimulate the plant's own defence mechanisms. The synthesis and biological activities of various benzo[1,2,3]thiadiazoles and related structures are described. S-Methyl benzo[1,2,3]thiadiazole-7-carbothioate is the first synthetic chemical 'plant activator' that has been developed for this novel disease control concept.