124461-27-4

Basic information

• Product Name: (2-BROMOPHENYL)(PYRROLIDIN-1-YL)METHANONE
• Synonyms: 1-(2-BROMOBENZOYL)PYRROLIDINE;(2-BROMOPHENYL)(PYRROLIDIN-1-YL)METHANONE;1-(PYRROLIDIN-1-YLCARBONYL)-2-BROMOBENZENE;1-(2-Bromobenzoyl)pyrrolidine 98%;1-(2-Bromobenzoyl)pyrrolidine98%
• CAS NO: 124461-27-4
• Molecular Formula: C₁₁H₁₂BrNO
• Molecular Weight: 254.12308
• Product Categories: blocks;Bromides;Carboxes;alkyl bromide
• Mol File: 124461-27-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 240-245/75mm
• Flash Point: 175.7 °C
• Appearance: /
• Density: 1.469 g/cm³
• Vapor Pressure: 1.41E-05mmHg at 25°C
• Refractive Index: 1.602
• Storage Temp.: Keep Cold
• CAS DataBase Reference: (2-BROMOPHENYL)(PYRROLIDIN-1-YL)METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (2-BROMOPHENYL)(PYRROLIDIN-1-YL)METHANONE(124461-27-4)
• EPA Substance Registry System: (2-BROMOPHENYL)(PYRROLIDIN-1-YL)METHANONE(124461-27-4)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 124461-27-4(Hazardous Substances Data)

Usage

General Description

(2-Bromophenyl)(pyrrolidin-1-yl)methanone is a chemical compound with the molecular formula C13H14BrNO. It is a white to pale yellow solid that is used in research and pharmaceutical applications. It is also known as α-pyrrolidinophenone or α-POP, and it is structurally related to the cathinone family of compounds. The compound has stimulant and psychoactive effects, and it has been found to act as a selective serotonin and dopamine releasing agent. It is not approved for medical use and is classified as a designer drug, often sold under names like "Flakka" or "Gravel". However, its use is associated with adverse effects and potential health risks.

InChI:InChI=1/C11H12BrNO/c12-10-6-2-1-5-9(10)11(14)13-7-3-4-8-13/h1-2,5-6H,3-4,7-8H2

Upstream product

• 123-75-1 pyrrolidine 
• 7154-66-7 2-bromobenzoic acid chloride 
• 15226-74-1 dicobalt octacarbonyl 
• 583-55-1 1-Bromo-2-iodobenzene 
• 6630-33-7 ortho-bromobenzaldehyde 

Downstream Products

• 91130-46-0 1-bromo-2-(pyrrolidin-1-ylmethyl)benzene 
• 2132-80-1 4,4'-Dimethoxybiphenyl 

Relevant articles and documents

Amide Bond Formation via Aerobic Photooxidative Coupling of Aldehydes with Amines Catalyzed by a Riboflavin Derivative

We report an effective, operationally simple, and environmentally friendly system for the synthesis of tertiary amides by the oxidative coupling of aromatic or aliphatic aldehydes with amines mediated by riboflavin tetraacetate (RFTA), an inexpensive organic photocatalyst, and visible light using oxygen as the sole oxidant. The method is based on the oxidative power of an excited flavin catalyst and the relatively low oxidation potential of the hemiaminal formed by amine to aldehyde addition.

Chiral sulfoxide ligands bearing nitrogen atoms as stereocontrollable coordinating elements in palladium-catalyzed asymmetric allylic alkylations

Palladium-catalyzed asymmetric allylic alkylations were studied by using chiral sulfoxide ligands bearing nitrogen atoms as coordinating elements, such as chiral α-sulfinylacetamides, β or γ-amino sulfoxides, and β- sulfinyl sulfonamides. The effects of t