1244958-70-0

Basic information

• Product Name: C₁₄H₁₉NO₅
• Synonyms: C₁₄H₁₉NO₅
• CAS NO: 1244958-70-0
• Molecular Weight: 281.309
• Mol File: 1244958-70-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₉NO₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₉NO₅(1244958-70-0)
• EPA Substance Registry System: C₁₄H₁₉NO₅(1244958-70-0)

Safety Data

• Hazardous Substances Data: 1244958-70-0(Hazardous Substances Data)

Upstream product

• 27025-24-7 Z-D-glutamic γ-methyl ester 
• 6461-04-7 (R)-2-amino-5-methoxy-5-oxopentanoic acid 
• 6893-26-1 D-Glutamic acid 
• 501-53-1 benzyl chloroformate 
• 67-56-1 methanol 

Downstream Products

• 1244958-71-1 C₂₀H₃₃NO₅Si 

Relevant articles and documents

Method for preparing azaindole compound

The invention provides a method for preparing an azaindole compound represented by a formula (I). According to the method, natural amino acid is used as a starting material to synthesize an intermediate defined in the specification, the intermediate reacts with 2-(N-tert-butyloxycarbonylamino)-3-methylpyridine in the presence of an organic alkali to obtain an intermediate defined in the specification, a protecting group is removed from the intermediate under an acidic condition, cyclization is performed to obtain an azaindole compound defined in the specification, and cyclization is performedthrough alcohol activating or a Mitsunobu reaction to obtain a compound represented by the formula (I). According to the method provided by the invention, natural amino acid is used as a starting material, so that complex processes such as chiral auxiliary synthesis, chiral resolution or introduction of chiral amino by enzyme catalytic reaction, and the like are avoided, the cost is greatly reduced, and the method is suitable for industrial large-scale production.