1245652-74-7

Upstream product

• 1149380-46-0 3-(imidazo[1,2-b]pyridazin-2-yl)benzonitrile 
• 6136-68-1 3-acethylbenzonitrile 
• 50916-55-7 3-(2-bromoacetyl)benzonitrile 
• 1125406-99-6 3-(6-chloro-imidazo[1,2-b]pyridazin-2-yl)-benzonitrile 

Downstream Products

• 1149380-45-9 2-(3-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl)imidazo[1,2-b]pyridazine 
• 1149380-51-7 2-(3-(5-(chloromethyl)-1,2,4-oxadiazol-3-yl)phenyl)imidazo[1,2-b]pyridazine 
• 1149380-50-6 N-((3-(3-(imidazo[1,2-b]pyridazin-2-yl)phenyl)-1,2,4-oxadiazol-5-yl)methyl)-2-methoxyethanamine 

Relevant academic research and scientific papers

CYTOKINE INHIBITORS

Provided is a compound of Formula (I): and/or at least one pharmaceutically acceptable salt thereof. Also provided are a method of inhibiting the activity of at least one protein chosen from TNFα, IL-1β, NF-κB, IL-10 and iNOS, a method of decreasing a lev

CYTOKINE INHIBITORS

A compound of Formula I: Each variable is defined in the specification. This invention relates to a method of decreasing a level of a cytokine (e.g., TNFα or interlukine such as IL-1β) in a subject with a compound of Formula I. It also relates to a method