50916-55-7

Basic information

• Product Name: 3-(2-Bromoacetyl)benzonitrile
• Synonyms: BUTTPARK 41\03-54;3-CYANOPHENACYL BROMIDE;3-(2-BROMOACETYL)BENZENECARBONITRILE;3-(2-BROMOACETYL)BENZONITRILE;3-(Bromoacetyl)benzonitrile;3-(2-Bromoacetyl)benzonitrile, 95+%;3-Cyanophenacyl bromide 95%;3-(2-Bromoacetyl)benzonitrile3-(2-Bromoacetyl)benzonitrile
• CAS NO: 50916-55-7
• Molecular Formula: C₉H₆BrNO
• Molecular Weight: 224.05
• Product Categories: Acetyl Halides;Phenyls & Phenyl-Het;Acetyl Halides;Phenyls & Phenyl-Het;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 50916-55-7.mol
• Article Data: 22

Chemical Properties

• Melting Point: 65-67°C
• Boiling Point: 317.7 °C at 760 mmHg
• Flash Point: 145.9 °C
• Appearance: /
• Density: 1.56 g/cm³
• Vapor Pressure: 0.000378mmHg at 25°C
• Refractive Index: 1.59
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: soluble in Methanol
• CAS DataBase Reference: 3-(2-Bromoacetyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-Bromoacetyl)benzonitrile(50916-55-7)
• EPA Substance Registry System: 3-(2-Bromoacetyl)benzonitrile(50916-55-7)

Safety Data

• Hazard Codes: C
• Statements: 20/21/22-34
• Safety Statements: 26-36/37/39-45
• RIDADR: 3261
• HazardClass: IRRITANT
• PackingGroup: III
• Hazardous Substances Data: 50916-55-7(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow solid

Uses

3-(2-Bromoacetyl)benzonitrile is used in the study of novel GSK-3 inhibitors as central nervous system agents.

InChI:InChI=1/C9H6BrNO/c10-5-9(12)8-3-1-2-7(4-8)6-11/h1-4H,5H2

Upstream product

• 6136-68-1 3-acethylbenzonitrile 
• 7726-95-6 bromine 

Downstream Products

• 136328-62-6 3-(2-Pyrrolidin-1-yl-acetyl)-benzonitrile 
• 6136-68-1 3-acethylbenzonitrile 
• 83112-49-6 α-acetoxy-3-cyanoacetophenone 
• 431040-28-7 3-(2-Methylimidazol-1-yl-acetyl)-benzonitrile 
• 722516-91-8 2-{[2-(3-cyanophenyl)-2-oxoethyl]thio}benzoic acid 
• 1055927-99-5 C₁₈H₁₂N₂O₂S 
• 202664-32-2 3-(2-aminothiazol-4-yl)benzonitrile 
• 288309-33-1 3-[2-(1H-1-pyrazolyl)acetyl]benzonitrile 
• 1125406-99-6 3-(6-chloro-imidazo[1,2-b]pyridazin-2-yl)-benzonitrile 
• 50916-56-8 2-(m-cyanophenyl)-2-oxoethylamine hydrochloride 

Relevant articles and documents

Based on isoxazole substitution of benzamide derivatives and anti-prostate cancer drug applications

The present invention discloses a class (I), formula (II) structure based on isoxazole substituted benzamide derivatives and antiprostate cancer drug applications, such isoxazole substituted benzamide derivatives, can effectively inhibit the activity of a

SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES

The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.

COMPOUNDS USEFUL AS RETINOID-RELATED ORPHAN RECEPTOR GAMMA MODULATORS

Disclosed are retinoid-related orphan receptor gamma (RORγ) modulators of Formula (I) and their use in the treatment of diseases mediated by RORγ, wherein the radicals have the meanings as defined in the invention.