1245657-05-9Relevant articles and documents
Targeted cutaneous delivery of ciclosporin A using micellar nanocarriers and the possible role of inter-cluster regions as molecular transport pathways
Lapteva, Maria,Santer, Verena,Mondon, Karine,Patmanidis, Ilias,Chiriano, Gianpaolo,Scapozza, Leonardo,Gurny, Robert,M?ller, Michael,Kalia, Yogeshvar N.
, p. 9 - 18 (2014)
Oral administration of ciclosporin A (CsA) is indicated in the treatment of severe recalcitrant plaque psoriasis. However, CsA is both nephro- and hepatotoxic and its systemic administration also exposes the patient to other severe side effects. Although