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1245735-33-4

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1245735-33-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1245735-33-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,5,7,3 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1245735-33:
(9*1)+(8*2)+(7*4)+(6*5)+(5*7)+(4*3)+(3*5)+(2*3)+(1*3)=154
154 % 10 = 4
So 1245735-33-4 is a valid CAS Registry Number.

1245735-33-4Relevant articles and documents

Tandem benzophenone amino pyridines, potent and selective inhibitors of human leukotriene C4 synthase

Kleinschmidt, Thea K.,Haraldsson, Martin,Basavarajappa, Devaraj,Lundeberg, Erik,Thulasingam, Madhuranayaki,Ekoff, Maria,Fauland, Alexander,Lehmann, Christoph,Kahnt, Astrid S.,Lindbom, Lennart,Haeggstr?m, Jesper Z.

, p. 108 - 116 (2015/09/28)

Cysteinyl leukotrienes (cys-LTs) are lipid mediators of inflammation. The enzyme catalyzing synthesis of cys-LTs, leukotriene C4 synthase (LTC4S), is considered an important drug target. Here we report the synthesis and characterization of thre

BIS AROMATIC COMPOUNDS FOR USE AS LTC4 SYNTHASE INHIBITORS

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Page/Page column 66, (2011/10/05)

There is provided compounds of formula (I): wherein E1, E2a, E2b, E2c, E4, D1, D2, D3, L1, Y1, L2 and Y2 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.

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