1245906-83-5Relevant academic research and scientific papers
Synthesis and in vitro activity of 4′ and 5′-modified analogues of apiosyl nucleosides as potent anti-HCV agents
Li, Hua,Lee, Wonjae,Hong, Joon Hee
, p. 1104 - 1116 (2009)
Novel doubly branched apio dideoxynucleosides were synthesized starting from 1,3-dihydroxyacetone using an ozonolysis and Grignard addition as key steps, and evaluated for anti-hepatitis C virus (HCV) activity. The adenine derivative 24 showed significant
