1246343-36-1

Basic information

• Product Name: Praziquantel-d11
• Synonyms: Praziquantel-d11;2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-(pyrazino-d11)[2,1-a]isoquinolin-4-one;Azinox-d11;Biltricide-d11;Cesol-d11;Cysticide-d11;Distocide-d11;Droncit-d11
• CAS NO: 1246343-36-1
• Molecular Formula: C₁₉H₂₄N₂O₂
• Molecular Weight: 312.40606
• Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals
• Mol File: 1246343-36-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Praziquantel-d11(CAS DataBase Reference)
• NIST Chemistry Reference: Praziquantel-d11(1246343-36-1)
• EPA Substance Registry System: Praziquantel-d11(1246343-36-1)

Safety Data

• WGK Germany: 1
• Hazardous Substances Data: 1246343-36-1(Hazardous Substances Data)

Usage

Description

Praziquantel-d11 is a labeled derivative of Praziquantel, an anthelmintic agent, which is used as an internal standard for the quantification of Praziquantel by gas chromatography (GC) or liquid chromatography (LC) mass spectrometry. It is an off-white solid and is effective against flatworms, particularly Schistosoma mansoni, a parasitic worm responsible for schistosomiasis.

Uses

Used in Pharmaceutical Industry:
Praziquantel-d11 is used as an internal standard for the quantification of Praziquantel by GCor LC-MS. This application is crucial in ensuring the accurate measurement and dosage of Praziquantel in pharmaceutical formulations, which is essential for the treatment of schistosomiasis.
Used in Veterinary Medicine:
As a labeled Praziquantel (P702095), Praziquantel-d11 is used as an anthelmintic, effective against flatworms. This application is particularly relevant in veterinary medicine, where it can be used to treat and prevent parasitic infections in animals.
Used in Research and Development:
Praziquantel-d11 can also be used in research and development for the study of Praziquantel's effects on various parasitic organisms. This can help in the development of new drugs and therapies for the treatment of parasitic infections.

Upstream product

• 93131-16-9 [1,2,2,3,3,4,4,5,5,6,6-2H₁₁]cyclohexanecarboxylic acid 
• 61196-37-0 2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one 

Relevant articles and documents

Methods of use comprising deuterated pyrazino[2,1-a]isoquinolines

This invention in one embodiment is directed to a compound of Formula Ia; where the designation (R) indicates that the designated carbon has the (R) stereochemistry; and wherein Z1 is hydrogen or fluorine; Z2 is hydrogen, deuterium,