1246382-96-6

Basic information

• Product Name: 4-{3-chloro-4-[3,3,3-trifluoro-2-hydroxy-2-(6-methoxy-pyridin-3-yl)-1-methyl-propyl]-phenoxy}-benzoic acid methyl ester
• Synonyms: 4-{3-chloro-4-[3,3,3-trifluoro-2-hydroxy-2-(6-methoxy-pyridin-3-yl)-1-methyl-propyl]-phenoxy}-benzoic acid methyl ester
• CAS NO: 1246382-96-6
• Molecular Weight: 495.883
• Mol File: 1246382-96-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-{3-chloro-4-[3,3,3-trifluoro-2-hydroxy-2-(6-methoxy-pyridin-3-yl)-1-methyl-propyl]-phenoxy}-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{3-chloro-4-[3,3,3-trifluoro-2-hydroxy-2-(6-methoxy-pyridin-3-yl)-1-methyl-propyl]-phenoxy}-benzoic acid methyl ester(1246382-96-6)
• EPA Substance Registry System: 4-{3-chloro-4-[3,3,3-trifluoro-2-hydroxy-2-(6-methoxy-pyridin-3-yl)-1-methyl-propyl]-phenoxy}-benzoic acid methyl ester(1246382-96-6)

Safety Data

• Hazardous Substances Data: 1246382-96-6(Hazardous Substances Data)

Upstream product

• 13780-71-7 dihydroxyborane 
• 1776-66-5 triisopropylborane 
• 1134915-79-9 3-(4-bromo-2-chloro-phenyl)-1,1,1-trifluoro-2-(6-methoxy-pyridin-3-yl)-butan-2-ol 

Relevant articles and documents

1,1,1-TRIFLUORO-2-HYDROXYPROPYL COMPOUNDS

The present invention relates to compounds of formula I wherein R1a to R1e and R2 to R5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as diabetes, dyslipidemia, obesity, hypertension, cardiovascular diseases, adrenal imbalance or depression.