124647-49-0

Basic information

• Product Name: N-(hydroxy-2' ethyl) amino-3 phenyl-3 propenoate d'ethyle
• Synonyms: N-(hydroxy-2' ethyl) amino-3 phenyl-3 propenoate d'ethyle
• CAS NO: 124647-49-0
• Molecular Weight: 235.283
• Mol File: 124647-49-0.mol

Chemical Properties

• CAS DataBase Reference: N-(hydroxy-2' ethyl) amino-3 phenyl-3 propenoate d'ethyle(CAS DataBase Reference)
• NIST Chemistry Reference: N-(hydroxy-2' ethyl) amino-3 phenyl-3 propenoate d'ethyle(124647-49-0)
• EPA Substance Registry System: N-(hydroxy-2' ethyl) amino-3 phenyl-3 propenoate d'ethyle(124647-49-0)

Safety Data

• Hazardous Substances Data: 124647-49-0(Hazardous Substances Data)

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 141-43-5 ethanolamine 

Downstream Products

• 38597-58-9 2-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester 
• 3042-22-6 2-phenyl-1H-pyrrole 
• 52179-74-5 5-phenyl-1H-pyrrole-2-carbaldehyde 
• 54799-75-6 formyl-1 phenyl-2 pyrrole 
• 52179-71-2 2-Phenyl-pyrrol-3-carbaldehyd 
• 20662-88-8 2-phenyloxazole 

Relevant articles and documents

IBX-Promoted Oxidative Cyclization of N-Hydroxyalkyl Enamines: A Metal-Free Approach toward 2,3-Disubstituted Pyrroles and Pyridines

An iodoxybenzoic acid-mediated selected oxidative cyclization of N-hydroxyalkyl enamines was developed. Through this strategy, a variety of 2,3-disubstituted pyrroles and pyridines were produced in good selectivity involving oxidation of alcohol, followed by condensation of aldehyde and α-C of enamines. Furthermore, this metal-free method has several advantages, including the use of environmentally friendly reagents, broad substrate scope, mild reaction conditions, and high efficiency.

SYNTHESE DE PYRROLES ET D'OXAZOLES PAR PYROLYSE DE N-(HYDROXY-2' ETHYL) AMINO-3 PROPENOATE

The gas phas pyrolysis of various N-(2'-hydroxyethyl)-3-amino propenoates 1-6 and N-(2'-hydroxy-2'-phenyl ethyl)-3-amino propanoate 7-9 at 390 deg C-420 deg C leads respectively to formylpyrroles 11-16 and benzoylpyrroles 17-19 and, in some cases, to substituted oxazoles 36-39.The results are best explained by the intermediate formation of a dicarbonyl derivative followed either by an intramolecular thermal crotonisation or a six ? electrocyclization of an azomethine ylide.