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38597-58-9

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38597-58-9 Usage

General Description

Ethyl 2-phenyl-1H-pyrrole-3-carboxylate, also known as ethyl 2-phenylpyrrole-3-carboxylate, is a chemical compound with the molecular formula C14H13NO2. It is a white to off-white crystalline powder that is used in the synthesis of pharmaceuticals and organic compounds. ethyl 2-phenyl-1H-pyrrole-3-carboxylate is also known for its potential biological activities, including its possible role as an antifungal, antibacterial, and antiviral agent. Ethyl 2-phenyl-1H-pyrrole-3-carboxylate is commonly used as a building block in organic chemistry for the preparation of various pyrrole derivatives, which have a wide range of applications in medicinal and materials science.

Check Digit Verification of cas no

The CAS Registry Mumber 38597-58-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,5,9 and 7 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 38597-58:
(7*3)+(6*8)+(5*5)+(4*9)+(3*7)+(2*5)+(1*8)=169
169 % 10 = 9
So 38597-58-9 is a valid CAS Registry Number.

38597-58-9Relevant articles and documents

IBX-Promoted Oxidative Cyclization of N-Hydroxyalkyl Enamines: A Metal-Free Approach toward 2,3-Disubstituted Pyrroles and Pyridines

Gao, Peng,Chen, Huai-Juan,Bai, Zi-Jing,Zhao, Mi-Na,Yang, Desuo,Wang, Juan,Wang, Ning,Du, Lele,Guan, Zheng-Hui

, p. 7939 - 7951 (2020/07/16)

An iodoxybenzoic acid-mediated selected oxidative cyclization of N-hydroxyalkyl enamines was developed. Through this strategy, a variety of 2,3-disubstituted pyrroles and pyridines were produced in good selectivity involving oxidation of alcohol, followed by condensation of aldehyde and α-C of enamines. Furthermore, this metal-free method has several advantages, including the use of environmentally friendly reagents, broad substrate scope, mild reaction conditions, and high efficiency.

One-Pot Synthesis of 3-Substituted 2-Arylpyrrole in Aqueous Media via Addition-Annulation of Arylboronic Acid and Substituted Aliphatic Nitriles

Yousuf, Md,Adhikari, Susanta

, p. 2214 - 2217 (2017/05/12)

Pd(II)-catalyzed C-C coupling reactions between substituted aliphatic nitriles and arylboronic acids followed by in situ cyclodehydration have been employed for the first time to synthesize a wide variety of 3-substituted 2-aryl-1H-pyrroles in aqueous acetic acid. This one-pot synthesis is green, and it conforms to atom economy. The structures of two representative pyrroles, 3k and 5f, were confirmed by X-ray crystallographic analysis.

SUBSTITUTED PYRROLES ACTIVE AS KINASES INHIBITORS

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Page/Page column 32, (2014/02/16)

The present invention relates to substituted pyrrole compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular Jak family kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them.

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