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2-Bromo-5-nitrobenzo[d]oxazole is a chemical compound characterized by the molecular formula C7H3BrN2O3. It is a nitroaromatic compound distinguished by the presence of a bromo group and a nitro group attached to a benzo[d]oxazole ring. 2-Bromo-5-nitrobenzo[d]oxazole is recognized for its unique chemical properties, making it a versatile building block in the synthesis of organic and pharmaceutical compounds.

1246472-00-3

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1246472-00-3 Usage

Uses

Used in Pharmaceutical Synthesis:
2-Bromo-5-nitrobenzo[d]oxazole is used as a key intermediate in the pharmaceutical industry for the production of various pharmaceuticals. Its unique structure allows for the creation of a wide range of medicinal compounds with diverse therapeutic applications.
Used in Agrochemical Production:
In the agrochemical sector, 2-Bromo-5-nitrobenzo[d]oxazole is utilized as a precursor in the synthesis of agrochemicals. Its properties contribute to the development of effective compounds for crop protection and pest control.
Used in Dye Manufacturing:
2-Bromo-5-nitrobenzo[d]oxazole is employed as a building block in the manufacturing of dyes. Its chemical structure lends itself to the creation of dyes with specific color characteristics and properties suitable for various applications.
Used in Antimicrobial Applications:
2-Bromo-5-nitrobenzo[d]oxazole is used as an antimicrobial agent due to its demonstrated ability to inhibit the growth of certain microorganisms. This makes it a valuable compound for research and development in the medical field, particularly for the creation of new antimicrobial drugs.
Used in Anti-inflammatory Research:
2-Bromo-5-nitrobenzo[d]oxazole's anti-inflammatory properties make it a promising candidate for research in the development of anti-inflammatory drugs. 2-Bromo-5-nitrobenzo[d]oxazole is used in the study of inflammation pathways and the design of new therapeutic agents to treat inflammatory conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 1246472-00-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,6,4,7 and 2 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1246472-00:
(9*1)+(8*2)+(7*4)+(6*6)+(5*4)+(4*7)+(3*2)+(2*0)+(1*0)=143
143 % 10 = 3
So 1246472-00-3 is a valid CAS Registry Number.

1246472-00-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Bromo-5-nitrobenzo[d]oxazole

1.2 Other means of identification

Product number -
Other names 2-bromo-5-nitro-1,3-benzoxazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1246472-00-3 SDS

1246472-00-3Downstream Products

1246472-00-3Relevant academic research and scientific papers

INHIBITORS OF HEPATITIS C VIRUS REPLICATION

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Paragraph 0914-0915, (2019/05/15)

The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

A method for the synthesis of 2-aminobenzoxazoles

Sherry, Benjamin D.,Chen, Yeo-Chuin Justin,Mangion, Ian K.,Yin, Jingjun

experimental part, p. 730 - 732 (2012/03/08)

A synthesis of 2-aminobenzoxazoles from the parent C-H compound is described. The procedure involves deprotonation at the 2-position of the benzoxazole and quenching the intermediate organolithium species with a halogen electrophile. The 2-halobenzoxazole is then treated in the same pot with an amine nucleophile to afford the desired product. The substrate scope and selectivity of the reaction are presented. The method is operationally simple and provides access to a variety of amine products bearing additional nucleophilic heteroatoms.

INHIBITORS OF HEPATITIS C VIRUS REPLICATION

-

Page/Page column 150, (2010/11/04)

The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

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