124658-79-3Relevant academic research and scientific papers
Sulfuric acid adsorbed on silica gel. A multipurpose acid catalyst
Chavez,Suarez,Diaz
, p. 2325 - 2339 (1994)
A series of acid catalyzed reactions like the dehydration of alcohols, conversion of ketones to 1,3-dioxolanes and their hydrolysis, α, β- unsaturated ketones to enol ethers, and alcohols to methyl-methoxyethyl ethers are performed efficiently in high yield with sulfuric acid adsorbed on silica gel as catalyst.
One-Pot Synthesis of Tetrahydrofuran Derivatives from Allylic Alcohols and Vinyl Ethers by Means of Palladium(II) Acetate
Fugami, Keigo,Oshima, Koichiro,Utimoto, Kiitiro
, p. 2050 - 2054 (2007/10/02)
Reaction of allylic alcohol with vinyl ether in the presence of Pd(OAc)2 afforded furan derivatives in good yield.Pd(OAc)2 was essential for the reaction.PdCl2 complex did not afford cyclized product but gave acetal exclusively.Three components were combined at once to produce 4-(3-butenyl)-2-butoxy-4-methyltetrahydrofuran upon treatment of a mixture of 2-methyl-2-propen-1-ol, butyl vinyl ether, and allyl bromide.The reaction could successfully be extended to the synthesis of nitrogen containing heterocycles by use of N-tosyl allylic amines in place of allylic alcohols.
ONE-POT SYNTHESIS OF TETRAHYDROFURAN DERIVATIVES FROM ALLYLIC ALCOHOLS AND VINYL ETHERS BY MEANS OF PALLADIUM(II) ACETATE
Fugami, Keigo,Oshima, Koichiro,Utimoto, Kiitiro
, p. 809 - 812 (2007/10/02)
Treatment of a mixture of allylic alcohol and vinyl ether in the presence of Pd(OAc)2 provides 2-alkoxy-4-alkenyltetrahydrofuran in good yield.
