7500-73-4

Basic information

• Product Name: 2-benzylhexan-1-ol
• CAS NO: 7500-73-4
• Molecular Formula: C₁₃H₂₀O
• Molecular Weight: 192.2973
• Mol File: 7500-73-4.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 298°C at 760 mmHg
• Flash Point: 118.7°C
• Density: 0.948g/cm³
• Vapor Pressure: 0.000584mmHg at 25°C
• Refractive Index: 1.508
• CAS DataBase Reference: 2-benzylhexan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzylhexan-1-ol(7500-73-4)
• EPA Substance Registry System: 2-benzylhexan-1-ol(7500-73-4)

Safety Data

• Hazardous Substances Data: 7500-73-4(Hazardous Substances Data)

Upstream product

• 66-25-1 hexanal 
• 100-51-6 benzyl alcohol 
• 109-72-8 n-butyllithium 
• 32571-10-1 4-chloro-6,6-dimethyl-2,5,6,7-tetrahydro-1H-azepin-2-one 
• 104-54-1 3-Phenylpropenol 
• 4510-34-3 (Z)-cinnamyl alcohol 
• 124658-79-3 (E)-3,3-dimethyl-7-phenyl-2,4-dioxahept-6-ene 
• 100-39-0 benzyl bromide 
• 7492-44-6 2-n-butyl-3-phenyl-2-propenal 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 4436-24-2 1,2-epoxy-3-phenylpropane 
• 1116-70-7 tri(n-butyl)aluminium 
• 114409-87-9 (2S)-2-Benzyl-1-hexanol 
• 5668-19-9 acide 2-benzyl-hexanoique 

Downstream Products

• 159213-11-3 (R)-2-Benzyl-hexanal 
• 7500-73-4 (2R)-2-Benzyl-1-hexanol 
• 114409-87-9 (2S)-2-Benzyl-1-hexanol 
• 5668-19-9 (2R)-2-Benzylhexanoic acid 
• 5668-19-9 (2S)-2-Benzylhexanoic acid 

Relevant articles and documents

Hydrogen borrowing catalysis using 1° and 2° alcohols: Investigation and scope leading to α and β branched products

The alkylation of a variety of ketones using 1° or 2° alcohols under hydrogen borrowing catalysis is described. Initial research focused on the α-alkylation of cyclopropyl ketones with higher 1° alcohols (i.e. larger than MeOH), leading to the formation of α-branched products. Our search for additional substrates with which to explore this chemistry led us to discover that di-ortho-substituted aryl ketones were also privileged scaffolds, with Ph? (C6Me5) ketones being the optimal choice. Further investigations revealed that this motif was crucial for alkylation with 2° alcohols forming β-branched products, which also provided an opportunity to study diastereoselective and intramolecular hydrogen borrowing processes.

Cross β-arylmethylation of alcohols catalysed by recyclable Ti-Pd alloys not requiring pre-activation

Ti-Pd alloy catalysts were developed for the cross β-arylmethylation between arylmethylalcohols and different primary alcohols via a hydrogen autotransfer mechanism. The alloy catalysts could be reused multiple times without the need for pre-activation. Analysis of the reaction solution by inductively coupled plasma atomic absorption spectroscopy indicated that only a minimal amount of Ti and no Pd was leached from the catalyst.

Enantioselective Formal α-Methylation and α-Benzylation of Aldehydes by Means of Photo-organocatalysis

Detailed herein is the photochemical organocatalytic enantioselective α-alkylation of aldehydes with (phenylsulfonyl)alkyl iodides. The chemistry relies on the direct photoexcitation of enamines to trigger the formation of reactive carbon-centered radicals from iodosulfones, while the ground-state chiral enamines provide effective stereochemical control over the radical trapping process. The phenylsulfonyl moiety, acting as a redox auxiliary group, facilitates the generation of radicals. In addition, it can eventually be removed under mild reducing conditions to reveal methyl and benzyl groups.