1246754-99-3

Upstream product

• 1443049-92-0 C₂₂H₃₉B₂NO₄Si 
• 3282-30-2 pivaloyl chloride 
• 100-52-7 benzaldehyde 
• 120419-97-8 (E)-N-benzylidene-1,1,1-trimethylsilanamine 
• 98-80-6 phenylboronic acid 
• 76-09-5 2,3-dimethyl-2,3-butane diol 

Downstream Products

• 1246755-13-4 (S)-(-)-N-[phenyl(3-thienyl)methyl]pivalamide 
• 1246755-14-5 (S)-(+)-N-[phenyl(3-pyridyl)methyl]pivalamide 
• 1246755-20-3 (S)-(+)-N-[(4-chlorophenyl)(phenyl)methyl]pivalamide 
• 1246755-06-5 (S)-(+)-N-[(4-ethoxycarbonylphenyl)(phenyl)methyl]pivalamide 
• 1246755-10-1 (S)-(-)-N-[(3-methylphenyl)(phenyl)methyl]pivalamide 
• 1246755-07-6 (S)-(+)-N-[(4-trifluoromethylphenyl)(phenyl)methyl]pivalamide 
• 1246755-09-8 (S)-(+)-N-[(4-formylphenyl)(phenyl)methyl]pivalamide 
• 1246755-08-7 (S)-(+)-N-[(4-acetylphenyl)(phenyl)methyl]pivalamide 
• 1246755-00-9 (S)-(-)-N-[(4-methylphenyl)(phenyl)methyl]pivalamide 

Relevant academic research and scientific papers

Catalytic enantioselective one-pot aminoborylation of aldehydes: A strategy for construction of nonracemic α-amino boronates

We report a strategy for the conversion of aldehydes to enantiomerically enriched α-amino boronates through the intermediacy of in situ-generated silylimines. This transformation is brought about by Pt-catalyzed asymmetric addition of B2(pin)s

Inversion or retention? Effects of acidic additives on the stereochemical course in enantiospecific suzuki-miyaura coupling of α-(acetylamino) benzylboronic esters

The stereochemical course of the stereospecific Suzuki-Miyaura coupling of enantioenriched α-(acetylamino)benzylboronic esters with aryl bromides can be switched by the choice of acidic additives in the presence of a Pd/XPhos catalyst system. Highly enant

Stereospecific Suzuki-Miyaura coupling of chiral α-(Acylamino) benzylboronic esters with inversion of configuration

The first invertive B-alkyl Suzuki-Miyaura coupling has been achieved. The coupling of enantioenriched α-(acylamino)benzylboronic esters with aryl bromides and chlorides took place efficiently in toluene at 80 °C in the presence of Pd(dba)2 (5 mol %), XPhos (10 mol %), K 2CO3 (3 equiv), and H2O (2 equiv). The reaction proceeded with inversion of configuration to give diarylmethanamine derivatives in high yields with high conservation of enantiomeric excesses.