124686-29-9

Basic information

• Product Name: Pentanoic acid, 3-methyl-4-oxo-, methyl ester, (S)- (9CI)
• Synonyms: Pentanoic acid, 3-methyl-4-oxo-, methyl ester, (S)- (9CI)
• CAS NO: 124686-29-9
• Molecular Formula: C7H12O3
• Molecular Weight: 144.16838
• Product Categories: ACETYLGROUP
• Mol File: 124686-29-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pentanoic acid, 3-methyl-4-oxo-, methyl ester, (S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanoic acid, 3-methyl-4-oxo-, methyl ester, (S)- (9CI)(124686-29-9)
• EPA Substance Registry System: Pentanoic acid, 3-methyl-4-oxo-, methyl ester, (S)- (9CI)(124686-29-9)

Safety Data

• Hazardous Substances Data: 124686-29-9(Hazardous Substances Data)

Upstream product

• 124686-35-7 (3S,4S)-4-Cyano-4-[((4R,5R)-2,2-dimethyl-4-phenyl-[1,3]dioxan-5-yl)-methyl-amino]-3,4-dimethyl-butyric acid methyl ester 
• 187737-37-7 propene 
• 201230-82-2 carbon monoxide 
• 67-56-1 methanol 
• 623-43-8 crotonic acid methyl ester 
• 53663-11-9 methyl (E)-3-methyl-4-oxopent-2-enoate 
• 53663-12-0 methyl 3-methyl-4-oxopent-2-enoate 

Relevant articles and documents

Biocatalytic access to nonracemic γ-oxo esters: Via stereoselective reduction using ene-reductases

The asymmetric bioreduction of α,β-unsaturated γ-keto esters using ene-reductases from the Old Yellow Enzyme family proceeds with excellent stereoselectivity and high conversion levels, covering a broad range of acyclic and cyclic derivatives. Various strategies were employed to provide access to both enantiomers, which are versatile precursors of bioactive molecules. The regioselectivity of hydride addition on di-activated alkenes was elucidated by isotopic labeling experiments and showed strong preference for the keto moiety as activating/binding group as opposed to the ester. Finally, chemoenzymatic synthesis of (R)-2-(2-oxocyclohexyl)acetic acid was achieved in high ee on a preparative scale combining enzymatic reduction followed by ester hydrogenolysis.

Highly enantioselective alternating copolymerization of propene with carbon monoxide catalyzed by a chiral phosphine-phosphite complex of palladium(II)

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