1248337-50-9Relevant academic research and scientific papers
Br?nsted acid-thiourea co-catalysis: Asymmetric synthesis of functionalized 1,4-dihydropyridines from β-enamino esters and α,β-unsaturated aldehydes
Yoshida, Kohzo,Inokuma, Tsubasa,Takasu, Kiyosei,Takemoto, Yoshiji
experimental part, p. 1865 - 1869 (2010/10/18)
A Br?nsted acid and a novel thiourea derivative co-catalyze the addition of β-enamino esters to α,β-unsaturated aldehydes leading to functionalized 1,4-dihydropyridines with moderate to good enantioselectivity. A regioselective synthesis of 1,2-dihydropyridines from α,β-unsaturated aldehydes is also described. Georg Thieme Verlag Stuttgart.
Catalytic asymmetric synthesis of both enantiomers of 4-substituted 1,4-Dihydropyridines with the use of bifunctional Thiourea-Ammonium salts bearing different counterions
Yoshida, Kohzo,Inokuma, Tsubasa,Takasu, Kiyosei,Takemoto, Yoshiji
experimental part, p. 8305 - 8326 (2011/03/17)
Organoammonium salts composed of a Bronsted acid and an anilinothiourea promoted the Michael addition of β-keto esters and α,β-unsaturated aldehydes in the presence of primary amines to give functionalized 1,4-dihydropyridines enantioselectively. With the
