124857-02-9Relevant academic research and scientific papers
Synthesis of dihydroquinolinones via iridium-catalyzed cascade C-H amidation and intramolecular aza-Michael addition
Pan, Changduo,Yang, Zhenkun,Xiong, Hao,Teng, Jiangang,Wang, Yun,Yu, Jin-Tao
supporting information, p. 1915 - 1918 (2019/05/02)
An iridium-catalyzed annulation of chalcones with sulfonyl azides via cascade C-H amidation and intramolecular aza-Michael addition was developed, affording a variety of 2-aryl-2,3-dihydro-4-quinolones in moderate to good yields. This reaction features ea
A Novel Aryl Rearrangement Reaction. Part 3. 2-Aryl Rearrangement in Azaflavanones
Zhao, Yajun,Yuan, Jinfang,Li, Liangzhu
, p. 28 - 29 (2007/10/03)
An aryl shift was observed when the trimethylsilyl enol ethers of azaflavanones were treated with iodosobenzeene-boron trifluoride, yielding aza-analogues of isoflavones and quinoline derivatives.
The Chemistry of 2'-Amino Analogues of 2'-Hydroxychalcone and Its Derivatives
Donnelly, John A.,Farrell, David F.
, p. 1757 - 1761 (2007/10/02)
The cyclization of 2'-aminochalcone (2a) and its side-chain additives has been studied for the development of syntheses of 2-aryl-4-quinolones. 2a and its 2'-acetamido 2b and 2'-benzenesulfonamido 2c derivatives underwent acid- or base-catalyzed cyclization to 1,2,3,4-tetrahydro-4-quinolones.The α,β-dibromides of 2b and 2c cyclized to cis-3-bromo-4-quinolones as did the corresponding α-bromochalcones and the α-bromo-β-methoxy additive of 2c. 2'-Acetamido-α-bromochalcone was cyclized by acid to 1,4-dihydro-2-phenyl-4-quinolone. 2'-Aminochalcone formed a stableepoxide which, with acid, gave cis-3-hydroxy-1,2,3,4-tetrahydro-3-phenyl-4-quinolone. 2'-Aminochalcones 2a-c and their additives, such as dibromide and epoxide, are useful, readily available precursors of various 2-aryl-4-quinolones.
