124864-15-9Relevant academic research and scientific papers
PYRIDINE ANCHORS FOR HMG-COA REDUCTASE INHIBITORS
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, (2008/06/13)
Compounds which are useful as inhibitors of cholesterol biosynthesis and thus as hypocholesterolemic agents are provided which have a quinoline or a pyridine anchor attached by means of a linker to a binding domain sidechain, which compounds inhibit the e
7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis
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, (2008/06/13)
Novel compounds for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis of the formula STR1 in which A, B, D and E can have varied meanings, X is --CH2 --CH2 or --CH=CH--, and R is STR2 wherein R21 denotes hyd
Phosphorus-Containing Inhibitors of HMG-CoA Reductase. 2. Synthesis and Biological Activites of a Series of Substituted Pyrydynes Containing a Hydroxyphosphinyl Moiety
Robl, Jeffrey A.,Duncan, Laurelee A.,Pluscec, Jelka,Karanevsky, Donald S.,Gordon, Eric M.,et al.
, p. 2804 - 2815 (2007/10/02)
A series of 2,3,4,(5),6-substituted pyridines containing a hydroxyphosphinyl functionality have been prepared and were evaluated for their ability to inhibit the enzyme HMG-CoA reductase.Systematic substitution of both R1-R4 and X-Y
CERTAIN 7-[2,6-DIISOPROPYL-4-PHENYL-5-LOWER ALKOXYMETHYL-PYRID-3-YL]-3,5-DIHYDROXY-6-ENOATES AND DERIVATIVES USEFUL FOR TREATING CIRCULATORY DISEASES
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, (2008/06/13)
Novel compounds for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis of the formula (I) in which A, B, D and E can have varied meanings, X is -CH2-CH2 or -CH=CH-, and R is wherein R21 denotes hydrogen or alkyl and R22 denotes hydrogen, denotes alkyl, aryl or aralkyl, or denotes a cation, and their oxidation products
