124901-76-4

Upstream product

• 124901-75-3 (2R,3R)-1-tosyloxy-2,3-decanediol 
• 77-76-9 2,2-dimethoxy-propane 
• 74867-37-1 (2R,3R)-1,2,3-Trihydroxydecane 
• 209479-89-0 (4R,5S,4'R)-5-((Z)-Hept-1-enyl)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl] 
• 209479-90-3 (4R,5S,4'R)-5-Heptyl-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl] 
• 13039-94-6 2,3,4,5-di-O-isopropylidene-D-xylose aldehyde 
• 81801-09-4 4-O-benzyl-2,3-O-isopropylidene-D-threose 
• 4762-26-9 hexyltriphenylphosphonium bromide 
• 252188-58-2 (4S,5R)-5-Heptyl-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid ethyl ester 
• 130967-61-2 [(4R,5R)-5-heptyl-2,2-dimethyl-1,3-dioxolan-4-yl]methanol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 239473-45-1 (3R,9S,10S)-10-tert-butyldimethylsilyloxy-3-tert-butyldiphenylsilyloxy-heptadec-1-ene-4,6-diyne-9-ol 
• 209479-94-7 (3R,9R,10R)-10-tert-butyldimethylsilyloxy-3-tert-butyldiphenylsilyloxy-heptadec-1-ene-4,6-diyne-9-ol 
• 87005-03-6 (3R,9R,10R)-panaxytriol 
• 128318-02-5 (2S,3S)-1-tosyloxy-2,3-decanediol 
• 124901-75-3 (2R,3R)-1-tosyloxy-2,3-decanediol 

Relevant academic research and scientific papers

Syntheses of two diastereoisomers of panaxytriol, a potent antitumor agent isolated from Panax ginseng

(3R, 9R, 10R) and (3R, 9S, 10S) diastereoisomers (2 and 3) of panaxytriol (1) were synthesized, and the absolute configuration of panaxytriol was confirmed as (3R, 9R, 10R)-heptadec-1-ene-4,6-diyne-3,9,10- triol.

Synthesis of a new type of antitumour agent panaxytriol: Synthesis of its four diastereomers

Synthesis of four diastereomers of panaxytriol has been described. The basic objective is to create two acetylenic precursors followed by cuprous chloride mediated C-C bond coupling reaction.

First total synthesis of panaxytriol, a potent antitumor agent isolated from Panax ginseng

Panaxytriol 1, a potent antitumor agent isolated from Panax ginseng, was first synthesized, and its stereostructure was confirmed to be (3R, 9R, 10R)-heptadec-1-ene-4,6-diyne-3,9,10-triol.

Synthesis and the Absolute Configuration of Panaxacol

Panaxacol, a polyacetylene isolated from the callus of Panax ginseng, was synthesized from D-(-)-diethyl tartrate.The absolute configuration of panaxacol was determined to be 9R,10R.