13039-94-6Relevant articles and documents
Fluorinated Ketene Dithioacetals. 3. A Radical Entry to α-Perfluoroalkyl Ketene Dithioacetals. Application to Sugar Derivatives.
Bergeron, S.,Brigaud, T.,Foulard, G.,Plantier-Royon, R.,Portella, C.
, p. 1985 - 1988 (1994)
α-Perfluoroalkyl ketene dithioacetals were synthesized by radical perfluoroalkylation of ketene dithioacetals with perfluoroalkyl iodide and sodium dithionite in a basic medium.Application to sugar derived ketene dithioacetals gave results depending strongly on the sugar structure. - Key-words: ketene dithioacetals, radical perfluoroalkylation, perfluoroalkylated sugars.
SUGAR-LINKER-DRUG CONJUGATES
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Paragraph 0202, (2014/09/29)
The present disclosure relates to sugar-linker-drug conjugates, of the formula [A-B-]n-L-D, wherein A is a saccharide; B is a spacer, n is an integer selected from 1 to 3; L is a linker group and D is a drug having a chemically reactive functional group selected from the group consisting of a primary or secondary amine, hydroxyl, sulfhydryl, carboxyl, aldehyde and ketone. Pharmaceutical compositions comprising the conjugates and methods of using thern are also provided.
trans-acetonide controlled endo-selective intramolecular nitrone-alkene cycloaddition of hept-6-enoses: A facile entry to calystegines, tropanes, and hydroxylated aminocycloheptanes
Shing, Tony K. M.,Wong, Wai F.,Ikeno, Taketo,Yamada, Tohru
, p. 207 - 209 (2007/10/03)
(Chemical Equation Presented) High-yielding endo-selective intramolecular nitrone-alkene cycloaddition (INAC) reactions of hept-6-enoses controlled by a trans-acetonide to give bridged bicyclo[4.2.1]isoxazolidines exclusively are realized for the first ti