124908-82-3Relevant academic research and scientific papers
A NEW TWO-CARBON OLEFIN HOMOLOGATION PROCEDURE THAT LEADS TO α-CHLOROENONES. AN EFFICIENT SYNTHESIS OF d,l-MUSCONE
Depres, Jean-Pierre,Navarro, Brigitte,Greene, Andrew E.
, p. 2989 - 2998 (1989)
Dichloroketene-olefin cycloadducts, α,α-dichlorocyclobutanones, are easily converted to α-chloroenones through a 3-step (2-pot) sequence of reactions.The overall result is the insertion of a functionalized 2-carbon unit between the original olefinic carbons.The efficiency of the method is demonstrated by a high-yield synthesis of d,l-muscone.
