124918-12-3Relevant academic research and scientific papers
Highly enantioselective intermolecular hydroamination of allylic amines with chiral aldehydes as tethering catalysts
MacDonald, Melissa J.,Hesp, Colin R.,Schipper, Derek J.,Pesant, Marc,Beauchemin, André M.
, p. 2597 - 2601 (2013/03/14)
Chirally LinkedIn: Chiral aldehydes are effective tethering catalysts for enantioselective intermolecular hydroamination, which provides access to vicinal diamine motifs in good yields and excellent enantioselectivities (see scheme). This work highlights simple chiral α-oxygenated aldehydes as effective organocatalysts capable of efficiently inducing asymmetry through transient intramolecularity. Copyright
Effect of substituent on the enantioselectivity for lipase-catalyzed kinetic resolution of glycerol derivatives
Kawanami, Yasuhiro,Honnma, Akira,Ohta, Kayo,Matsumoto, Naoko
, p. 693 - 697 (2007/10/03)
The lipase-catalyzed transesterifications of various substituted diphenyl 1,2-ketals of glycerol have been investigated. Efficient modification of the substrate structure with bis(4-bromophenyl) ketal was found to enhance the enantioselectivity up to E=57
Organocatalytic kinetic resolution of racemic primary alcohols using a chiral 1,2-diamine derived from (S)-proline
Terakado, Dai,Koutaka, Hitomi,Oriyama, Takeshi
, p. 1157 - 1165 (2007/10/03)
A highly efficient and good enantioselective organocatalytic asymmetric acylation of racemic primary alcohols with acyl chlorides has been achieved catalyzed by a chiral 1,2-diamine derived from (S)-proline.
