1252016-87-7Relevant academic research and scientific papers
Selective palladium-catalyzed aminocarbonylation of 1,3-dienes: Atom-efficient synthesis of β,γ-unsaturated amides
Fang, Xianjie,Li, Haoquan,Jackstell, Ralf,Beller, Matthias
supporting information, p. 16039 - 16043 (2015/02/19)
Carbonylation reactions constitute important methodologies for the synthesis of all kinds of carboxylic acid derivatives. The development of novel and efficient catalysts for these transformations is of interest for both academic and industrial research. Here, the first palladium-based catalyst system for the aminocarbonylation of 1,3-dienes is described. This atom-efficient transformation proceeds under additive-free conditions and provides straightforward access to a variety of β,γ-unsaturated amides in good to excellent yields, often with high selectivities.
Remarkable levels of enantioswitching in catalytic asymmetric hydroboration
Smith, Sean M.,Takacs, James M.
supporting information; experimental part, p. 4612 - 4615 (2010/12/19)
TADDOL-derived phosphites and phosphoramidites are effective ligands for rhodium-catalyzed asymmetric hydroborations of β,γ-unsaturated amides, achieving up to 99% ee. However, the sense of stereoinduction, R or S, is surprisingly dependent on rather subt
