125208-77-7

Basic information

• Product Name: (E)-5-(4-chlorostyryl)-1-phenyl-1H-tetrazole
• Synonyms: (E)-5-(4-chlorostyryl)-1-phenyl-1H-tetrazole
• CAS NO: 125208-77-7
• Molecular Weight: 282.732
• Mol File: 125208-77-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-5-(4-chlorostyryl)-1-phenyl-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-5-(4-chlorostyryl)-1-phenyl-1H-tetrazole(125208-77-7)
• EPA Substance Registry System: (E)-5-(4-chlorostyryl)-1-phenyl-1H-tetrazole(125208-77-7)

Safety Data

• Hazardous Substances Data: 125208-77-7(Hazardous Substances Data)

Upstream product

• 24721-26-4 4-chlorochalcone 
• 6948-68-1 1-chloro-4-(3-phenyl-2-propen-1-yl)benzene 
• 100-52-7 benzaldehyde 

Relevant articles and documents

A facile and convenient synthesis of substituted tetrazole derivatives from ketones or α,β-unsaturated ketones.

Triazidochlorosilane (SiCl4-NaN3 in situ) is a new and efficient reagent for the direct conversion of ketones or α,β-unsaturated ketones to the corresponding tetrazole derivatives in nearly quantitative yield.

Implanting nitrogen into hydrocarbon molecules through Ci-H and Ci-C bond cleavages: A direct approach to tetrazoles

From simple beginnings: A novel Cu-promoted direct incorporation of nitrogen into simple hydrocarbon molecules under mild and neutral reaction conditions is described. 1,5-Disubstituted tetrazoles are efficiently constructed by two C sp 3i-H and one Ci-C bond cleavages (see scheme; TMS=trimethylsilyl). This protocol provides a new and unique strategy to functionalize simple and readily available hydrocarbon molecules.