125225-28-7

Basic information

• Product Name: IPCONAZOLE
• Synonyms: IPCONAZOLE;ipconazole (bsi, pa e-iso);knf-317;IPCONAZOLE STANDARD;2-((4-Chlorophenyl)methyl)-5-(1-methylethyl)-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol;Cyclopentanol, 2-((4-chlorophenyl)methyl)-5-(1-methylethyl)-1-(1H-1,2,4-triazol-1-ylmethyl)-;Ipconazole [iso]
• CAS NO: 125225-28-7
• Molecular Formula: C₁₈H₂₄ClN₃O
• Molecular Weight: 333.861
• Mol File: 125225-28-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 86～92℃
• Boiling Point: 486°Cat760mmHg
• Flash Point: 247.7°C
• Appearance: /
• Density: 1.24g/cm³
• Vapor Pressure: 2.94E-10mmHg at 25°C
• Refractive Index: 1.617
• PKA: 13.76±0.60(Predicted)
• Water Solubility: 6.93 mg l-1 (20 °C)
• CAS DataBase Reference: IPCONAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: IPCONAZOLE(125225-28-7)
• EPA Substance Registry System: IPCONAZOLE(125225-28-7)

Safety Data

• Hazardous Substances Data: 125225-28-7(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 125225-28-7 differently. You can refer to the following data:
1. Ipconazole controls a wide range of seed diseases in rice and other crops and is particularly effective against 'Bakanae disease', Helminthosporum leaf spot and blast on rice.
2. Ipconazole is a fungicide used in pesticide compositions.

Definition

ChEBI: A member of the class of cyclopentanols carrying 1,2,4-triazol-1-ylmethyl, 4-chlorobenzyl and isopropyl substituents at positions 1, 2 and 5 respectively. Used to control a range of seed diseases in rice, vegetables and other, mainly non-food, crops.

Metabolic pathway

Ipconazole is a mixture of two geometric isomer pairs (lRS,2SR,5RS) (I) and (lRS,2SR,5SR) (Ⅱ). They differ in the orientation of the hydroxy, benzyl and isopropyl groups. The ratio of I : II in the technical product is 90 : 10 and the two-component isomer pairs are of equal activity. The metabolism of ipconazole in plants and animals involves oxidation at the benzylic and isopropyl groups to yield alcohols which may be further oxidised to the corresponding ketones or carboxylic acids (or lactones). The resulting array of metabolites can be expected to be stereochemically more complex than the original isomer mixture.

Degradation

Ipconazole is stable towards hydrolysis and is thermally stable.

InChI:InChI=1/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3

Upstream product

• 41253-21-8 sodium triazole 
• 25596-24-1 trimethyloxosulfonium bromide 
• 288-88-0 1,2,4-Triazole 
• 872-50-4 1-methyl-pyrrolidin-2-one 

Relevant articles and documents

Synthesis method of triazole bactericide

The invention relates to a triazole bactericide synthesis method, which comprises: (a) mixing a cyclopentanone compound, a solid alkali, 1,2,4-triazole sodium and an organic solvent, stirring, heating, introducing an inert gas, carrying out bubbling dehydration, and adding trimethyl sulfoxide halide to form a reaction system so as to carry out a reaction; and (b) stopping introduction of the inertgas when the content of the cyclopentanone compound in the reaction system is lower than 1%, and sequentially concentrating, recrystallizing and drying to obtain the triazole bactericide. Compared with the prior art, the method simplifies the reaction process, is safer and more environment-friendly, reduces the production cost, and is convenient for industrial production.

Synergistic Active Compound Combinations Comprising Phenyltriazoles

The present invention relates to novel active compound combinations comprising, firstly, at least one known compound of the formula (I) in which R1 and R2 have the meanings given in the description. and at least one further known active compound from groups (2) to (27) listed in the description, which combinations are highly suitable for controlling animal pests such as insects and unwanted acarids and also phytopathogenic fungi.