125289-66-9Relevant articles and documents
Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist
Epifano, Francesco,Genovese, Salvatore,James Squires,Gray, Matthew A.
scheme or table, p. 3130 - 3135 (2012/06/04)
A series of 29 oxyprenylated and azoprenylated phenylpropanoids were chemically synthesized and tested in transfected cultured HepG2 cells by means of the dual-luciferase assay as farnesoid X receptor (FXR) agonists, using the endogenous ligand chenodeoxy
An efficient and chemoselective cleavage of prenyl ethers with DDQ
Vatéle, Jean-Michel
, p. 507 - 509 (2007/10/03)
The prenyl (Pre) protecting group tor hydroxyl functions is readily removed at room temperature with DDQ in dichloromethane-water (9:1). The reaction conditions are compatible with the presence of other ethereal functionalities such as acetonides, allyl, benzyl, TBS, TBDPS groups. We have also shown that Sdeprotection of prenyl ethers using a catalytic amount of DDQ in the presence of 3 equivalents of Mn(OAc)3 is a good alternative for the use of a stoichiometric amount of DDQ, albeit the reaction time being longer.