125290-60-0

Basic information

• Product Name: 1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• Synonyms: 1-(2,4-Difluorophenyl)-6-fluoro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
• CAS NO: 125290-60-0
• Molecular Formula: C₂₂H₂₀F₃N₃O₃
• Molecular Weight: 431.4077
• Mol File: 125290-60-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 641.2°C at 760 mmHg
• Flash Point: 341.6°C
• Density: 1.397g/cm³
• Vapor Pressure: 2.55E-17mmHg at 25°C
• Refractive Index: 1.598
• CAS DataBase Reference: 1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(125290-60-0)
• EPA Substance Registry System: 1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(125290-60-0)

Safety Data

• Hazardous Substances Data: 125290-60-0(Hazardous Substances Data)

Usage

Type of Drug

Synthetic 4th generation fluoroquinolone antibiotic

Mechanism of Action

Inhibits bacterial DNA replication and protein synthesis by inhibiting bacterial topoisomerase IV and DNA gyrase

Effective Against

Wide range of gram-positive and gram-negative bacteria, including those resistant to other antibiotics

Indications

Respiratory tract infections, skin and soft tissue infections, and urinary tract infections

Forms Available

Tablet and liquid forms

Side Effects

Nausea, diarrhea, and dizziness

Drug Group

Fluoroquinolones

Usage

Treats various bacterial infections

Tolerance

Generally well-tolerated

Resistance

Effective against bacteria resistant to other antibiotics

Prescription

Typically prescribed by healthcare professionals for serious infections

Upstream product

• 109-07-9 (RS)-2-methylpiperazine 
• 119916-37-9 ethyl 6,7-difluoro-1-(2,4-difluorophenyl)-1,4-dihydro-5-methyl-4-oxo-3-quinolinecarboxylate 

Relevant articles and documents

Synthesis and Biological Activity of 5-Alkyl-1,7,8-trisubstituted-6-fluoroquinoline-3-carboxylic Acids

A series of 5-alkyl-1,7,8-trisubstituted-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids was prepared and evaluated for in vitro and in vivo antibacterial activity.When compared to the 5-hydrogen analogues, the presence of the 5-methyl group enhanc