1253047-01-6

Basic information

• Product Name: (DL)-N-benzyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
• Synonyms: (DL)-N-benzyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
• CAS NO: 1253047-01-6
• Molecular Weight: 280.326
• Mol File: 1253047-01-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (DL)-N-benzyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (DL)-N-benzyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-3-carboxamide(1253047-01-6)
• EPA Substance Registry System: (DL)-N-benzyl-1-oxo-1,2,3,4-tetrahydroisoquinoline-3-carboxamide(1253047-01-6)

Safety Data

• Hazardous Substances Data: 1253047-01-6(Hazardous Substances Data)

Upstream product

• 61650-22-4 N-(pivaloyloxy)benzamide 
• 13304-62-6 N-benzylacrylamide 
• 495-18-1 Benzohydroxamic acid 
• 63586-82-3 1-Oxo-1,2,3,4-tetrahydro-3(R,S)-isoquinolinecarboxylic Acid 
• 100-46-9 benzylamine 

Relevant articles and documents

Design and synthesis of dihydroisoquinolones for fragment-based drug discovery (FBDD)

This study describes general synthesis aspects of fragments for FBDD, as illustrated by the dihydroisoquinolones 1-3. Previous Rh(iii) methodology is extended to incorporate amines, heteroatoms (N and S), and substituents (halogen, ester) as potential binding groups and/or synthetic growth points for fragment-to-lead elaboration.