125340-68-3Relevant academic research and scientific papers
Stereoselective total synthesis of (+)-anamarine via cross-metathesis protocol
Sabitha, Gowravaram,Reddy, C. Nagendra,Gopal, Peddabuddi,Yadav
scheme or table, p. 5736 - 5739 (2010/11/16)
A convergent stereoselective total synthesis of (+)-anamarine via cross-metathesis (CM) protocol starting from 2-butyn-1,4-diol and vinyl lactone is reported. Other key features of the strategy include the use of Sharpless asymmetric epoxidation, Sharples
AN ENANTIOCONTROLLED ROUTE TO THE C11-17 SEGMENT OF MYCINAMICINS III AND IV
Takano, Seiichi,Sekiguchi, Yoshinori,Ogasawara, Kunio
, p. 743 - 756 (2007/10/02)
An enantiocontrolled route to the common C11-17 segment (2) of mycinamicins III (1a) and IV (1b) has been developed starting from the chiral α-hydroxyacetylene (6) obtained from (E)-4-benzyloxybut-2-en-1-ol (3).
Enantiodivergent Route to the Aromatic Bisabolane Sesquiterpenes via a Chiral Acetylene Alcohol
Takano, Seiichi,Sugihara, Takumichi,Samizu, Kiyohiro,Akiyama, Masashi,Ogasawara, Kunio
, p. 1781 - 1784 (2007/10/02)
Efficient preparation and practical utilization of (R)-1-benzyloxy-3-butyn-2-ol have been established.Treatment of (2S,3S)-4-benzyloxy-2,3-epoxybutyl chloride, obtained via the Sharpless epoxidation, with n-butyllithium afforded (R)-1-benzyloxy-3-butyn-2-
Asymmetric Construction of Optically Active 3-Hydroxyalkyne Functionalities
Takano, Seiichi,Samuzi, Kiyohiro,Sugihara, Takumichi,Ogasawara, Kunio
, p. 1344 - 1345 (2007/10/02)
An efficient method for the construction of optically active 3-hydroxyalkyne functionalities has been developed using optically active α,β-epoxy alcohols readily accessible from non-chiral allyl alcohol precursors.
