125342-95-2

Upstream product

• 50493-59-9 2-hydroxy-6-methoxynaphthalene-1-carbaldehyde 
• 100-39-0 benzyl bromide 
• 107-03-9 1-thiopropane 
• 55218-08-1 2,6-dimethoxy-1-naphthalenecarbaldehyde 
• 584-08-7 potassium carbonate 

Downstream Products

• 125342-94-1 N-[[6-Methoxy-2-(phenylmethoxy)-5-(trifluoromethyl)-1-naphthalenyl]carbonyl]-N-methylglycine Methyl Ester 
• 124323-67-7 [(2-Benzyloxy-6-methoxy-5-trifluoromethyl-naphthalene-1-carbothioyl)-methyl-amino]-acetic acid 
• 134057-63-9 [(2-Benzyloxy-6-methoxy-5-trifluoromethyl-naphthalene-1-carbonyl)-methyl-amino]-acetic acid 
• 134057-89-9 2-Benzyloxy-6-methoxy-naphthalene-1-carboxylic acid 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships of 2-amino-1- aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents

A series of aroylnaphthalene derivatives were prepared as bioisosteres of combrestatin A-4 and evaluated for anticancer activity. 2-Amino-1- aroylnaphthalene and 2-hydroxy-1-aroylnaphthalene, 9 and 8, respectively, showed strong antiproliferative activity

Syntheses of tolrestat analogues containing additional substituents in the ring and their evaluation as aldose reductase inhibitors. Identification of potent, orally active 2-fluoro derivatives

A series of aldose reductase inhibitors were prepared which were analogues of the potent, orally active inhibitor tolrestat (1). These compounds (5, 7, 9, and 10) have an extra substituent on one of the unoccupied positions on the naphthalene ring of 1. P

Production of N-((2-alkoxy-6-methoxy-5-(trifluoromethyl)-1-naphthalenyl)carbonyl)-N-methylglycine esters

Process for the production of N-[[2-alkoxy-6-methoxy-5-(trifluoromethyl)-1-naphthalenyl]carbonyl]-N-methylglycine esters and intermediates for their production. Said esters are themselves intermediates for the manufacture of compounds which inhibit aldose