1253432-99-3

Upstream product

• 1253430-02-2 3-(1-ethyl-3,4-dimethylpyrazol-5-yl)-2-(4-tertbutylphenyl)-3-hydroxyl-acrylonitrile 
• 3282-30-2 pivaloyl chloride 
• 3288-99-1 4-tert-butylbenzyl cyanide 
• 1253433-77-0 methyl 1-ethyl-3,4-dimethylpyrazol-5-ylcarboxylate 

Relevant academic research and scientific papers

Synthesis, Acaricidal Activity, and Structure-Activity Relationships of Pyrazolyl Acrylonitrile Derivatives

A series of novel pyrazolyl acrylonitrile derivatives was designed, targeting Tetranychus cinnabarinus, and synthesized. Their structures were identified by combination of1H NMR,13C NMR, and MS spectra. The structures of compounds 18 and 19 were further confirmed by X-ray diffraction. Extensive greenhouse bioassays indicated that compound 19 exhibits excellent acaricidal activity against all developmental stages of T. cinnabarinus, which is better than the commercialized compounds cyenopyrafen and spirodiclofen. It was shown that the acute toxicity of compounds 19 to mammals is quite low. The structure-activity relationships are also discussed.

Pyrazolyl Acrylonitrile Compounds and Uses Thereof

A kind of pyrazolyl acrylniitrile compounds represented by the structures of formula I or stereoisomers thereof are disclosed in the present invention. Where in: R1 is selected from the group of substituents consisting of H, C1-Csub