3226-15-1

Basic information

• Product Name: 1-(2-hydroxyphenyl)hexan-1-one
• Synonyms: 1-(2-hydroxyphenyl)hexan-1-one
• CAS NO: 3226-15-1
• Molecular Weight: 192.258
• Mol File: 3226-15-1.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 1-(2-hydroxyphenyl)hexan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-hydroxyphenyl)hexan-1-one(3226-15-1)
• EPA Substance Registry System: 1-(2-hydroxyphenyl)hexan-1-one(3226-15-1)

Safety Data

• Hazardous Substances Data: 3226-15-1(Hazardous Substances Data)

Upstream product

• 7780-16-7 phenyl hexanoate 
• 59648-34-9 1-(2-hydroxyphenyl)-1-hexanol 
• 119-36-8 methyl salicylate 
• 611-20-1 salicylonitrile 
• 693-25-4 n-pentylmagnesium bromide 
• 1646629-15-3 chloro(pentyl)diphenylsilane 
• 19311-91-2 N,N-diethylsalicylamide 
• 108-95-2 phenol 
• 65009-00-9 O-phenyl N,N-diethylcarbamate 
• 3525-31-3 n-pentyl lithium 
• 125345-27-9 2-(hex-1-yn-1-yl)phenol 
• 555-16-8 4-nitrobenzaldehdye 
• 142-62-1 hexanoic acid 
• 95255-51-9 (-)-2-{1-{[(1R)-1-phenylethyl]imino}ethyl}phenol 

Downstream Products

• 17508-91-7 4,6-Dinitro-2-(1-pentylheptyl)-phenol 
• 17508-90-6 4,6-Dinitro-2-(1-pentylhexyl)-phenol 
• 17508-87-1 4,6-Dinitro-2-(1-butylhexyl)-phenol 
• 17404-55-6 2-(1-Pentylheptyl)-phenol 
• 17404-54-5 2-(1-Pentylhexyl)-phenol 
• 17404-51-2 2-(5-decyl)phenol 
• 204859-45-0 1-(2-Hydroxy-phenyl)-hexan-1-one oxime 
• 17403-79-1 2-<1-Pentyl-hexen-(1)-yl>-phenol 
• 17403-80-4 4-(1-Pentylhept-1-enyl)-phenol 
• 17403-78-0 2-<1-Pentyl-penten-(1)-yl>-phenol 

Relevant articles and documents

Aroyl Fluorides as Bifunctional Reagents for Dearomatizing Fluoroaroylation of Benzofurans

The 2,3-dihydrobenzofuran scaffold is widely found in natural products and biologically active compounds. Herein, dearomatizing 2,3-fluoroaroylation of benzofurans with aroyl fluorides as bifunctional reagents to access 2,3-difunctionalized dihydrobenzofurans is reported. The reaction that occurs by cooperative NHC/photoredox catalysis provides 3-aroyl-2-fluoro-2,3-dihydrobenzofurans with moderate to good yield and high diastereoselectivity. Cascades proceed via radical/radical cross-coupling of a benzofuran radical cation generated in the photoredox catalysis cycle with a neutral ketyl radical formed through the NHC catalysis cycle. The redox-neutral transformation exhibits broad substrate scope and high functional group compatibility. With anhydrides as bifunctional reagents, dearomatizing aroyloxyacylation of benzofurans is achieved and the strategy can also be applied to N-acylated indoles to afford 3-aroyl-2-fluoro-dihydroindoles.

Piperidine-mediated annulation of 2-acylphenols with 4-nitrobenzaldehyde to 3-benzofuranones

Piperidine - mediated reactions of 2-acylphenols and 4-nitrobenzaldehydes afforded 3-benzofuranones in high yield (82-95%) at reflux temperature in ethanol. The electron density calculation of HOMO-LUMO energy in the chalcone intermediates by DFT showed t

TMSOTf-promoted addition of alkynes to aldehydes: A novel synthesis of chroman-4-ones

A novel synthetic method to prepare chalcones 2 and chroman-4-ones 3 by TMSOTf-promoted addition of alkynes 1 to various aldehydes has been developed. The ratios of chalcones 2, chroman-4-ones 3 and hydrated products 4 varied depending upon the substituents R (nBu, phenyl, H and TMS) on the alkynes 1. We also describe the transformation of the chalcones 2 to the corresponding chroman-4-ones 3 under basic conditions. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.