1253799-29-9 Usage
Uses
Used in Pharmaceutical Industry:
2-Benzyloxy-3-dibenzylaMino-5-fluoro-6-Methyl-benzoic acid phenyl ester is used as a building block for the synthesis of tetracycline antibiotics. Its unique molecular structure allows for the creation of various tetracycline derivatives with improved properties, such as enhanced antibiotic activity, better bioavailability, and reduced side effects.
The compound's role in the synthesis of tetracycline antibiotics is crucial, as it can be used to modify the core structure of these drugs, potentially leading to the development of new and more effective treatments for bacterial infections. By incorporating 2-Benzyloxy-3-dibenzylaMino-5-fluoro-6-Methyl-benzoic acid phenyl ester into the synthesis process, researchers can explore new ways to combat antibiotic resistance and improve the overall effectiveness of tetracycline-based therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 1253799-29-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,3,7,9 and 9 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1253799-29:
(9*1)+(8*2)+(7*5)+(6*3)+(5*7)+(4*9)+(3*9)+(2*2)+(1*9)=189
189 % 10 = 9
So 1253799-29-9 is a valid CAS Registry Number.
1253799-29-9Relevant academic research and scientific papers
SYNTHESIS OF TETRACYCLINES AND INTERMEDIATES THERETO
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, (2010/11/17)
The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides more efficient routes for preparing the enone intermediate and allows for substituents at positions 4a, 5, 5a, and 12a of the tetracycline ring system.
