1254271-32-3

Upstream product

• 551-93-9 2-aminoacetophenone 
• 2142-70-3 2-iodoacetophenone 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 1135136-54-7 2-(4-methoxyphenyl)thiochroman-4-one 
• 893-10-7 2-(4'-methoxyphenyl)-4H-1-benzothiopyran-4-one 
• 118485-45-3 (E)-2-(4-methoxybenzylidene)-3-phenyl-2,3-dihydro-1H-inden-1-one 

Relevant academic research and scientific papers

Copper-Catalyzed Domino Synthesis of 2-Arylthiochromanones through Concomitant C-S Bond Formations Using Xanthate as Sulfur Source

An efficient domino process for the synthesis of thioflavanones has been described using a copper catalyst without addition of any external ligand. A variety of thioflavanones have been synthesized from easily accessible 2′-iodochalcones or 2′-bromochalco

COMPOSITION FOR TREATING DIABETES AND METABOLIC DISEASES AND A PREPARATION METHOD THEREOF

Disclosed is a chalcone composition for treating diabetes and metabolic syndromes. In particular, the chalcone compound bound with 2-halogen in ring A significantly decreases the blood glucose level in the in vitro anti-diabetic effect experiment. In the in vivo animal model, the leading chalcone compound can prevent the progression of diabetes and control the blood glucose level, and there is no significant difference in the gains in body weight. Throughout the seven-week administration, there are no hepatic or renal toxicity observed.