1254708-85-4Relevant academic research and scientific papers
Synthesis of a series of novel chiral Lewis base catalysts and their application in promoting asymmetric hydrosilylation of β-enamino esters
Chen, Xing,Hu, Xiao-Yan,Shu, Chang,Zhang, Yong-Hong,Zheng, Yong-Sheng,Jiang, Yan,Yuan, Wei-Cheng,Liu, Bo,Zhang, Xiao-Mei
supporting information, p. 3089 - 3093 (2013/06/04)
A series of novel chiral Lewis base catalysts were synthesized from l-serine and applied in the hydrosilylation of β-enamino esters, in which the optimal one promoted the reactions to afford a wide variety of β-amino esters in good yields with good enantioselectivities. It is noteworthy that several cyclic substrates were hydrosilylated under the optimal conditions to give the cyclic β-amino esters with high yields, good diastereoselectivities as well as good ee values. The Royal Society of Chemistry 2013.
Highly diastereoselective and enantioselective synthesis of α-hydroxy β-amino acid derivatives: Lewis base catalyzed hydrosilylation of α-acetoxy β-enamino esters
Jiang, Yan,Chen, Xing,Zheng, Yongsheng,Xue, Zhouyang,Shu, Chang,Yuan, Weicheng,Zhang, Xiaomei
, p. 7304 - 7307 (2011/09/16)
By design: A series of α-acetoxy-β-enamino esters 1 were synthesized and then subjected to catalytic asymmetric hydrosilylation. In the presence of a chiral Lewis base catalyst, the reactions proceeded smoothly to provide a wide range of chiral α-acetoxy β-amino acid derivatives in high yields with good diastereoselectivities and enantioselectivities. Copyright
A strategy to synthesize taxol side chain and (-)-epi cytoxazone via chiral Bronsted acid-Rh2(OAc)4 Co-catalyzed enantioselective three-component reactions
Qian, Yu,Xu, Xinfang,Jiang, Liqin,Prajapati, Dipak,Hu, Wenhao
scheme or table, p. 7483 - 7486 (2011/02/21)
A new approach to synthesize optically active β-amino-α-hydroxyl acid derivatives via chiral Bronsted acid-Rh2(OAc) 4 cocatalyzed three-component reactions of diazo acetates with alcohols and imines is reported. A matched reaction sy
